The predictive value of serum concentrations of anti-Mullerian hormone for oocyte quality, fertilization, and implantation

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dc.citation.issue3]
dc.citation.volume21]
dc.contributor.authorBorges, Edson
dc.contributor.authorBraga, Daniela P. A. F. [UNIFESP]
dc.contributor.authorSetti, Amanda
dc.contributor.authorFigueira, Rita de Cassia
dc.contributor.authorIaconelli, Assumpto, Jr.
dc.coverageRibeirao
dc.date.accessioned2020-06-26T16:30:23Z
dc.date.available2020-06-26T16:30:23Z
dc.date.issued2017
dc.description.abstractObjective: This study aimed to identify a possible correlation between serum levels of anti-.Mullerian hormone (AMH) and oocyte quality, embryo developmental competence, and implantation potential. Methods: 4488 oocytes obtained from 408 patients undergoing ICSI cycles were evaluated. Oocyte dimorphisms, embryo quality on days two and three, blastocyst formation competence, fertilization rates, implantation rates, and pregnancy rates were correlated with serum levels of AMH using Pearson's correlation coefficient and regression analysis. Results: A positive correlation was observed between serum levels of AMH and number of retrieved oocytes (CC: 0.600, p<0.001), fertilization rate (CC: 0.595, p=0.048), and number of obtained embryos (CC: 0.495, p<0.001). AMH did not affect the quality of cleavage stage embryos or the chance of blastocyst formation. However, AMH levels affected oocyte quality (OR: 0.75, CI 0.44-.0.96, p<0.001), and implantation (CC: 0,116, p=0.031) and pregnancy (OR: 1.22, CI: 1.03-.1.53, p<0.001) rates. Conclusion: Serum levels of AMH are a useful predictor of ovarian response to COS, oocyte quality, and fertilization. However, AMH levels may also compromise clinical outcomesen
dc.description.abstractlower AMH levels did not impair embryo development.en
dc.description.affiliationFertil Med Grp, Sao Paulo, SP, Brazil
dc.description.affiliationCtr Estudos & Pesquisa Reprod Assistida, Inst Sapientiae, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Cirurgia, Area Reprod Humana, Disciplina Urol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Cirurgia, Area Reprod Humana, Disciplina Urol, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent176-182
dc.identifierhttp://dx.doi.org/10.5935/1518-0557.20170035]
dc.identifier.citationJornal Brasileiro De Reproducao Assistida. Ribeirao, v. 21, n. 3, p. 176-182, 2017.
dc.identifier.doi10.5935/1518-0557.20170035
dc.identifier.fileWOS000411259400003.pdf
dc.identifier.issn1517-5693
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53513
dc.identifier.wosWOS:000411259400003
dc.language.isoeng
dc.publisherSoc Brasileira Reproducao Assistida-Sbra
dc.relation.ispartofJornal Brasileiro De Reproducao Assistida
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectOocyteen
dc.subjectblastocysten
dc.subjectembryo implantationen
dc.subjectpregnancyen
dc.subjectCOS cellsen
dc.subjectanti-Mullerian hormoneen
dc.titleThe predictive value of serum concentrations of anti-Mullerian hormone for oocyte quality, fertilization, and implantationen
dc.typeinfo:eu-repo/semantics/article
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