Gap junctions between mast cells and fibroblasts in the developing avian eye

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dc.contributor.authorOliani, Sonia Maria [UNIFESP]
dc.contributor.authorGirol, Ana Paula [UNIFESP]
dc.contributor.authorSmith, Ricardo Luiz [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T11:14:54Z
dc.date.available2018-06-15T11:14:54Z
dc.date.issued1995-01-01
dc.description.abstractMast cells are present in the eye of chick embryos from the 14th day onward, displaying metachromatic granules, mainly in the iris anterior surface and pectinate ligament, Ultrastructurally these cells show electron-dense granules and a few thin and short cytoplasmic projections in close contact with fibroblasts. Sometimes these contacts are extensive, with long fibroblast projections partially involving the mast cells. Gap junctions between mast cells and fibroblasts are observed only in the eyes of 16- and 20-day-old embryos. These intercellular specializations are represented by a close apposition of cytoplasmic membranes with an extension up to 300 nm. Gap junctions between mast cells and fibroblasts were not observed previously in vivo or in vitro, although in vitro studies have shown that a number of functionally critical interactions may occur between these cells. Our morphological findings suggest that, in vivo, fibroblasts interact with mast cells and may influence their maturation.en
dc.description.affiliationUNIFESP,ESCOLA PAULISTA MED,DEPT MORPHOL,SAO PAULO,BRAZIL
dc.description.affiliationUNIFESP,ESCOLA PAULISTA MED,CTR ELECTRON MICROSCOPY,SAO PAULO,BRAZIL
dc.description.affiliationUnifespUNIFESP,ESCOLA PAULISTA MED,DEPT MORPHOL,SAO PAULO,BRAZIL
dc.description.affiliationUnifespUNIFESP,ESCOLA PAULISTA MED,CTR ELECTRON MICROSCOPY,SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent267-271
dc.identifierhttp://dx.doi.org/10.1159/000147778
dc.identifier.citationActa Anatomica. Basel: Karger, v. 154, n. 4, p. 267-271, 1995.
dc.identifier.doi10.1159/000147778
dc.identifier.issn0001-5180
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/41970
dc.identifier.wosWOS:A1995UM16700003
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofActa Anatomica
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectmast cellen
dc.subjectfibroblasten
dc.subjectgap junctionen
dc.subjecteyeen
dc.subjectdevelopmenten
dc.subjectchicken
dc.titleGap junctions between mast cells and fibroblasts in the developing avian eyeen
dc.typeinfo:eu-repo/semantics/article
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