New Strategy for Controlled Release of Nitric Oxide
Data
2012-01-01
Autores
Seabra, Amedea B. 
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Nitric oxide (NO) is involved in several physiological processes, such as the control of vascular tone, the inhibition of platelet aggregation, smooth muscle cell replication, immune response and neuronal communication. Several pathologies have been associated to dysfunctions in the endogenous NO production. Thus, there is a great interest in the development of NO-releasing drugs and in matrices which are able to stabilize and release NO locally in different tissues. in this scenario, the preparation of NO-releasing nanomaterials, such as dendrimers, liposomes, metallic, silica, and polymeric nanoparticles, zeolites and metal organic frameworks, is a promising strategy for delivering NO in diverse applications, as discussed in this work.
Descrição
Citação
Journal of Nano Research. Stafa-zuerich: Trans Tech Publications Ltd, v. 20, p. 61-67, 2012.