Histopathological diagnosis of corneal button specimens: An epidemiological study

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dc.contributor.authorGodeiro, Katyanne D. [UNIFESP]
dc.contributor.authorCoutinho, Anamaria B. [UNIFESP]
dc.contributor.authorPereira, Patricia da Rocha [UNIFESP]
dc.contributor.authorFernandes, Bruno F. [UNIFESP]
dc.contributor.authorCassie, Amanda
dc.contributor.authorBurnier, Miguel Noel Nascente [UNIFESP]
dc.contributor.institutionHenry C Witelson Ocular Pathol Lab
dc.contributor.institutionMcGill Univ
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:41:45Z
dc.date.available2016-01-24T12:41:45Z
dc.date.issued2007-01-01
dc.description.abstractPurpose: To determine the most common histopathological diagnosis of corneal specimens from penetrating keratoplasty (PKP). Methods: the records of 500 corneal specimens submitted to biopsy at the Henry Witelson Ocular Pathology Laboratory, Montreal, Canada, from 1999 to 2004 were reviewed. Age, sex, clinical indications, and histopathological findings were analyzed. Results: Chronic keratitis (45.6%) was the most common pathological diagnosis, followed by corneal edema (25.8%), dystrophy (12.8%), keratoconus (KC) (9.2%), acute keratitis (5.6%), and degeneration (1.0%). Among the specimens with chronic keratitis, regraft was the most common clinical indication (39.0%). in the group of acute keratitis, ulcerative condition was the leading cause (75,0%). Fuchs' endothelial dystrophy represented 79.7% of the clinical diagnoses in the group of corneal dystrophies. the median patient age was 70-79 years, and the gender distribution was nearly symmetric. Conclusion: the present study is important for determining the most common histopathological diagnoses of corneal button specimens and the correlation with the age, gender, and clinical indications of PKP.en
dc.description.affiliationHenry C Witelson Ocular Pathol Lab, Dept Ophthalmol & Pathol, Montreal, PQ H3A 2B4, Canada
dc.description.affiliationMcGill Univ, Ctr Hlth, Montreal, PQ, Canada
dc.description.affiliationUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent70-75
dc.identifierhttp://dx.doi.org/10.1080/09286580600954330
dc.identifier.citationOphthalmic Epidemiology. Philadelphia: Taylor & Francis Inc, v. 14, n. 2, p. 70-75, 2007.
dc.identifier.doi10.1080/09286580600954330
dc.identifier.issn0928-6586
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/29403
dc.identifier.wosWOS:000246298600003
dc.language.isoeng
dc.publisherTaylor & Francis Inc
dc.relation.ispartofOphthalmic Epidemiology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.subjectcornealen
dc.subjectdiagnosisen
dc.subjectepidemiologicalen
dc.subjecthistopathologicalen
dc.subjectspecimensen
dc.titleHistopathological diagnosis of corneal button specimens: An epidemiological studyen
dc.typeinfo:eu-repo/semantics/article
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