Usefulness of waist circumference as a marker of abdominal adiposity in peritoneal dialysis: a cross-sectional and prospective analysis

dc.contributor.authorBazanelli, Ana Paula [UNIFESP]
dc.contributor.authorKamimura, Maria Ayako [UNIFESP]
dc.contributor.authorManfredi, Silvia Regina [UNIFESP]
dc.contributor.authorDraibe, Sergio Antonio [UNIFESP]
dc.contributor.authorCuppari, Lilian [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:17:49Z
dc.date.available2016-01-24T14:17:49Z
dc.date.issued2012-02-01
dc.description.abstractWaist circumference (WC) has been well recognized as a surrogate marker of abdominal adiposity. in peritoneal dialysis (PD) patients, however, aspects related to this dialysis modality, such as abdominal distension, presence of catheter and frequent hernia, raise questions regarding the reliability of WC measurements. Herein, we investigated for the first time whether WC is a reliable marker of abdominal adiposity in PD population.This study included 107 prevalent PD patients [56% male, age 52 +/- 17 years, 35% diabetics, body mass index (BMI) 24.8 +/- 3.9 kg/m(2)]. WC measured at umbilicus level was evaluated against the trunk fat assessed by dual-energy x-ray absorptiometry at baseline and after 6 months. All measurements were taken with the empty abdominal cavity.At baseline, a strong correlation of WC with trunk fat (r = 0.81; P < 0.001) was observed. Adjusting for gender, age, dialysis vintage and BMI, WC was independently associated with trunk fat (beta = 0.30; P < 0.001; R-2 = 0.77). the agreement between WC and trunk fat was 0.59 (kappa statistic) and the area under the curve was 0.90. in the prospective evaluation, we observed that changes in WC correlated with changes in trunk fat as well (r = 0.49; P < 0.001). the kappa statistic of 0.48 remained indicative of a moderate agreement between the methods. the receiver operating characteristic curve analysis showed that WC was sensitive to detect changes in trunk fat (area under the curve 0.76). in the logistic regression analysis adjusting for gender, age and BMI, changes in WC were independently associated with changes in trunk fat.The simple anthropometric method of WC is a reliable marker of abdominal adiposity in PD patients.en
dc.description.affiliationUniversidade Federal de São Paulo, Nutr Program, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Div Nephrol, Dept Med, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Nutr Program, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Nephrol, Dept Med, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipClinical Evidence Council (Baxter Healthcare Corporation)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipOswaldo Ramos Foundation
dc.format.extent790-795
dc.identifierhttp://dx.doi.org/10.1093/ndt/gfr361
dc.identifier.citationNephrology Dialysis Transplantation. Oxford: Oxford Univ Press, v. 27, n. 2, p. 790-795, 2012.
dc.identifier.doi10.1093/ndt/gfr361
dc.identifier.issn0931-0509
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34546
dc.identifier.wosWOS:000300421300051
dc.language.isoeng
dc.publisherOxford Univ Press
dc.relation.ispartofNephrology Dialysis Transplantation
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.oxfordjournals.org/access_purchase/self-archiving_policyb.html
dc.subjectabdominal adiposityen
dc.subjectchronic kidney diseaseen
dc.subjectperitoneal dialysisen
dc.subjecttrunk faten
dc.subjectwaist circumferenceen
dc.titleUsefulness of waist circumference as a marker of abdominal adiposity in peritoneal dialysis: a cross-sectional and prospective analysisen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções