Argon plasma versus electrofulguration in the treatment of anal and perianal condylomata acuminata in patients with acquired immunodeficiency virus

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dc.citation.issue6]
dc.citation.volume32]
dc.contributor.authorBraga, Eduardo Angelo [UNIFESP]
dc.contributor.authorLopes Filho, Gaspar de Jesus [UNIFESP]
dc.contributor.authorSaad, Sarhan Sydney [UNIFESP]
dc.coverageSao Paulo
dc.date.accessioned2020-06-26T16:30:41Z
dc.date.available2020-06-26T16:30:41Z
dc.date.issued2017
dc.description.abstractPurpose: To compare the effectiveness of anal and perianal condylomata treatment using argon plasma and electrofulguration. Methods: From January 2013 to April 2014, 37 patients with anal and perianal condylomata, who had been diagnosed through proctological examination, oncotic cytology, polymerase chain reaction (PCR) and histology, underwent treatment with argon plasma and electrofulguration. The perianal and anal regions were divided into two semicircles. Each semicircle was treated using one of the methods by means of simple randomization. Therapeutic sessions were repeated until all clinical signs of infection by HPV were eliminated. The patients were evaluated according to several variables like the genotype of HPV, HIV infection, oncological potential per genotype, oncotic cytology and histology. Results: Among all the variables studied, only immunosuppression due to HIV influenced the results, specifically when the fulguration method was used. There was no significant difference in effectiveness between argon and fulguration based on lesion relapse (p > 0.05). However, among HIV-positive patients, fulguration presented worse results, with a significant difference (p = 0.01). Conclusion: Regarding treatment of anal and perianal condylomata acuminata, comparison between applying fulguration and argon demonstrated that these methods were equivalent, but use of fulguration presented more relapses among HIV-positive patients.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Med Sch, Postgrad Program Interdisciplinary Surg Sci, Dept Surg,Div Surg Gastroenterol, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Med Sch, Dept Surg, Div Surg Gastroenterol, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Escola Paulista Med, Postgrad Program Interdisciplinary Surg Sci, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Med Sch, Postgrad Program Interdisciplinary Surg Sci, Dept Surg,Div Surg Gastroenterol, Sao Paulo, SP, Brazill
dc.description.affiliationUnifespUniv Fed Sao Paulo, Med Sch, Dept Surg, Div Surg Gastroenterol, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Escola Paulista Med, Postgrad Program Interdisciplinary Surg Sci, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent482-490
dc.identifierhttp://dx.doi.org/10.1590/s0102-865020170060000009]
dc.identifier.citationActa Cirurgica Brasileira. Sao Paulo, v. 32, n. 6, p. 482-490, 2017.
dc.identifier.doi10.1590/s0102-865020170060000009
dc.identifier.fileS0102-86502017000600482.pdf
dc.identifier.issn0102-8650
dc.identifier.scieloS0102-86502017000600482
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/53699
dc.identifier.wosWOS:000405403200009
dc.language.isoeng
dc.publisherActa Cirurgica Brasileira
dc.relation.ispartofActa Cirurgica Brasileira
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCondylomata Acuminataen
dc.subjectArgon Plasma Coagulationen
dc.subjectElectrosurgeryen
dc.subjectPapillomaviridaeen
dc.subjectHIV Seropositivityen
dc.titleArgon plasma versus electrofulguration in the treatment of anal and perianal condylomata acuminata in patients with acquired immunodeficiency virusen
dc.typeinfo:eu-repo/semantics/article
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