Severity scoring of atopic dermatitis: a comparison of two scoring systems

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dc.contributor.authorRullo, V. E. V. [UNIFESP]
dc.contributor.authorSegato, A. [UNIFESP]
dc.contributor.authorKirsh, A. [UNIFESP]
dc.contributor.authorSole, D. [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:51:32Z
dc.date.available2016-01-24T13:51:32Z
dc.date.issued2008-07-01
dc.description.abstractBackground: Atopic dermatitis (AD) is a chronic inflammatory pruritic skin heterogeneous disease, which does not have an objective tool able to permit comparison between patients and to monitor changes due to a specific treatment. Several assessment methods have been developed to evaluate the AD.Objectives: the aim of this study was to investigate the agreement between two observers in the assessment of the severity of AD applying SCORAD index and EASI in infants and young children with AD. the variations of parameters that compose each score, as well as the inter-observer variation for both scores, were also studied.Methods: We evaluated 42 infants and young children admitted and followed in a paediatric allergy centre (UNIFESP-EPM). All children met the diagnostic criteria for clinical AD established by Hanifin and Rajka. Two investigators graded the severity of AD, applying the SCORAD index and EASI. the two scoring systems assessed the variation between baseline evaluation and one month after treatment.Results: Significant correlations were observed comparing both scores for each physician and each evaluation. There were no differences between the mean SCORAD and EASI scores for each physician, in the two evaluations. There was a significant decrease in the mean total SCORAD and EASI score and its components, except for the item Upper Extremities EASIConclusion: Both scoring systems for AD are valid, reproducible and responsive in monitoring AD patients. Further studies will be necessary to investigate the development of AD and the best evaluation. SCORAD showed itself to be an excellent score to detect the development of AD, whereas the EASI are suitable to follow up in drug-effect studies of AD for research purposes.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent205-211
dc.identifierhttp://dx.doi.org/10.1016/S0301-0546(08)72551-5
dc.identifier.citationAllergologia Et Immunopathologia. Barcelona: Elsevier Doyma Sl, v. 36, n. 4, p. 205-211, 2008.
dc.identifier.doi10.1016/S0301-0546(08)72551-5
dc.identifier.issn0301-0546
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30782
dc.identifier.wosWOS:000260621000006
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofAllergologia Et Immunopathologia
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectAtopic dermatitisen
dc.subjectScoreen
dc.subjectSeverityen
dc.subjectScoring systemen
dc.titleSeverity scoring of atopic dermatitis: a comparison of two scoring systemsen
dc.typeinfo:eu-repo/semantics/article
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