Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients

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dc.contributor.authorMonteiro Junior, Francisco das Chagas [UNIFESP]
dc.contributor.authorCunha Junior, Cacionor Pereira da
dc.contributor.authorMuniz Ferreira, Pedro Antonio
dc.contributor.authorTeixeira Nunes, Jose Aldemir
dc.contributor.authorBrito, Ronald Lopes
dc.contributor.authorBarbosa, Jose Bonifacio
dc.contributor.authorMandarino, Natalia Ribeiro
dc.contributor.authorLages, Joyce Santos
dc.contributor.authorSalgado Filho, Natalino
dc.contributor.authorLima, Valter Correia de [UNIFESP]
dc.contributor.institutionUniv Fed Maranhao
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:34:44Z
dc.date.available2016-01-24T14:34:44Z
dc.date.issued2013-12-01
dc.description.abstractIntroduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.en
dc.description.affiliationUniv Fed Maranhao, Univ Hosp, Serv Cardiol, Sao Luis, Maranhao, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent975-980
dc.identifierhttp://dx.doi.org/10.1016/j.repc.2013.04.016
dc.identifier.citationRevista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013.
dc.identifier.doi10.1016/j.repc.2013.04.016
dc.identifier.issn0870-2551
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37000
dc.identifier.wosWOS:000329949300004
dc.language.isopor
dc.publisherElsevier B.V.
dc.relation.ispartofRevista Portuguesa de Cardiologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectHypertensionen
dc.subjectCarotid intima-media thicknessen
dc.subjectRisk assessmenten
dc.titlePrevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patientsen
dc.typeinfo:eu-repo/semantics/article
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