Renal abnormalities in Ankylosing Spondylitis

Página do item simplificado
dc.contributor.authorVilar, Maria José Pereira [UNIFESP]
dc.contributor.authorCury, Silvia Elisa [UNIFESP]
dc.contributor.authorFerraz, Marcos Bosi [UNIFESP]
dc.contributor.authorSesso, Ricardo de Castro Cintra [UNIFESP]
dc.contributor.authorAtra, Edgard [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-18T12:11:52Z
dc.date.available2018-06-18T12:11:52Z
dc.date.issued1997-01-01
dc.description.abstractRenal abnormalities have been reported in Ankylosing Spondylitis (AS) patients. Possible mechanisms include the effects of nonsteroidal anti-inflammatory drugs (NSAIDs), an increased incidence of glomerulonephritis, particularly the ones associated with deposition of IgA-containing immune complexes and the renal deposition of amyloid. These observations prompted us to evaluate in detail the frequency and severity of renal dysfunction in 40 AS patients, consecutively selected attending the rheumatology disease unit outpatient clinic at Escola Paulista de Medicina, using sensitive tests of glomerular and tubular function. Fourteen of the 40 patients presented one or more signs of renal involvement: microscopic hematuria (9 patients), microalbuminuria (4 patients), decreased renal function assessed by serum creatinine (2 patients), and creatinine clearance (4 patients). None of the patients presented increased urinary excretion of retinol binding protein (RBP). The finding of renal abnormalities in 35% of our patients suggests that in this illness evidence of renal involvement should be actively investigated.en
dc.description.affiliationUNIV FED SAO PAULO,ESCOLA PAULISTA MED,DIV RHEUMATOL,BR-04023062 SAO PAULO,BRAZIL
dc.description.affiliationUNIV FED SAO PAULO,ESCOLA PAULISTA MED,DEPT MED,DIV NEPHROL,BR-04023062 SAO PAULO,BRAZIL
dc.description.affiliationUnifespUNIV FED SAO PAULO,ESCOLA PAULISTA MED,DIV RHEUMATOL,BR-04023062 SAO PAULO,BRAZIL
dc.description.affiliationUnifespUNIV FED SAO PAULO,ESCOLA PAULISTA MED,DEPT MED,DIV NEPHROL,BR-04023062 SAO PAULO,BRAZIL
dc.description.sourceWeb of Science
dc.format.extent19-23
dc.identifierhttp://dx.doi.org/10.3109/03009749709065659
dc.identifier.citationScandinavian Journal Of Rheumatology. Oslo: Scandinavian University Press, v. 26, n. 1, p. 19-23, 1997.
dc.identifier.doi10.3109/03009749709065659
dc.identifier.issn0300-9742
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/45575
dc.identifier.wosWOS:A1997WJ29700004
dc.language.isoeng
dc.publisherScandinavian University Press
dc.relation.ispartofScandinavian Journal Of Rheumatology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAnkylosing Spondylitisen
dc.subjectrenal abnormalitiesen
dc.subjecthematuriaen
dc.subjectmicroalbuminuriaen
dc.titleRenal abnormalities in Ankylosing Spondylitisen
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos