Functional capacity after pediatric liver transplantation: A pilot study

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dc.contributor.authorSilva, Rosangela Maria da [UNIFESP]
dc.contributor.authorCarvalho, Werther Brunow de
dc.contributor.authorJohnston, Cintia [UNIFESP]
dc.contributor.authorCastro, Mariela Borba de [UNIFESP]
dc.contributor.authorFerreira, Israel Manta [UNIFESP]
dc.contributor.authorPatti, Camilla L. [UNIFESP]
dc.contributor.authorAzevedo, Ramiro Anthero de [UNIFESP]
dc.contributor.authorGonzalez, Adriano Miziara [UNIFESP]
dc.contributor.authorLinhares, Marcelo Moura [UNIFESP]
dc.contributor.authorSalzedas-Netto, Alcides Augusto [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2016-01-24T14:37:50Z
dc.date.available2016-01-24T14:37:50Z
dc.date.issued2014-09-01
dc.description.abstractThe prospective cross-sectional study investigated the 6MWT performance in pediatric group of liver transplant recipients (6-17 yr, median post-transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6MWT. We analyzed the relationship between walked distance and the 6MWw, distance walked x body weight) with the anthropometric, clinical, and pulmonary functions. in post-transplanted group, the average walked distance was significantly shorter compared with control (687 +/- 80 m vs. 511 +/- 72 m, p < 0.001). the calculated ICC coefficient confirmed the reproducibility among tests. the Pearson correlation revealed that only walked distance in the 6MWT was moderately correlated with tidal volume. Conversely, the 6MWw was significantly correlated with age, weight, height, BMI, FVC, PEF rate, and volume expiratory. According to multiple regression analysis, age, VE and FVC factors explained 80% of the variance in the 6MWw. in conclusion, the pediatric liver transplant recipients' performance in the 6MWT is significantly lower than the values for healthy children of the same age. Notably, the 6MWw may provide relevant information, constituting an additional parameter in the determination of functional capacity.en
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Pediat, BR-04304000 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Intens Care Neonatol Childrens Inst, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Pharmacol, BR-04304000 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Surg, Div Pediat Liver Transplantat, BR-04304000 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Pediat, BR-04304000 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Pharmacol, BR-04304000 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Surg, Div Pediat Liver Transplantat, BR-04304000 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent586-593
dc.identifierhttp://dx.doi.org/10.1111/petr.12318
dc.identifier.citationPediatric Transplantation. Hoboken: Wiley-Blackwell, v. 18, n. 6, p. 586-593, 2014.
dc.identifier.doi10.1111/petr.12318
dc.identifier.issn1397-3142
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38197
dc.identifier.wosWOS:000340530800014
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofPediatric Transplantation
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.subjectliver transplantationen
dc.subjectstress testen
dc.subjectphysical fitnessen
dc.subjectreproducibilityen
dc.subjectChildrenen
dc.subjectsix-min walk testen
dc.titleFunctional capacity after pediatric liver transplantation: A pilot studyen
dc.typeinfo:eu-repo/semantics/article
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