Anemia reduction in preschool children with the addition of low doses of iron to school meals

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dc.contributor.authorArcanjo, Francisco Placido Nogueira [UNIFESP]
dc.contributor.authorPinto, Vicente de Paulo Teixeira
dc.contributor.authorCoelho, M. R.
dc.contributor.authorAmancio, Olga Maria Silverio [UNIFESP]
dc.contributor.authorMagalhaes, S. M. M.
dc.contributor.institutionUniv Fed Ceara
dc.contributor.institutionSecretariat Educ Sobral
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:51:36Z
dc.date.available2016-01-24T13:51:36Z
dc.date.issued2008-08-01
dc.description.abstractBackground. in developing countries there is high prevalence of iron deficiency anemia, which causes negative impact on growth, development and quality of life for infant population. Currently several strategies are being elaborated and tested to tackle this problem. Objective. To measure anemia prevalence in preschool children. To evaluate fortification effectiveness with 5 or 10 mg of elemental iron/daily added to school meals by increasing hemoglobin levels in anemic children. Methods. Double-blind, cluster randomized intervention study with 728 students from public network. Blood count was taken at beginning of study, to evaluate anemia prevalence, those anemic were selected for intervention, after intervention new blood count was taken to evaluate fortification effectiveness. Ferrous Sulphate was added in individual dosage of 5 or 10 mg of elemental iron/daily to usual school meal. From 35 schools 3 were randomized to receive 5 mg/daily (group A) and 3 to receive 10 mg/daily (group B). Hemoglobin and hematocrit averages before and after intervention were compared in each group and between them. Results. in group A, the anemia prevalence reduced 34.9 to 12.4%, and in group B 39.0 to 18.7%. in both groups a significant increase in hemoglobin was observed: in group A from 10.1 to 11.5 g/dl (p < 0.01) and in group B from 10.0 to 11.0 g/dl (p < 0.01). There was no statistically significant difference in final levels of hemoglobin among groups. Conclusions. Both dosages of elemental iron were equally effective in increasing hemoglobin levels, and reducing anemia prevalence. Fortification of school meals was shown to be an effective, low cost and easy to manage intervention.en
dc.description.affiliationUniv Fed Ceara, Fac Med, Sobral Unit, BR-62010100 Sobral, Ceara, Brazil
dc.description.affiliationSecretariat Educ Sobral, BR-62011060 Sobral, Ceara, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Res Lab, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniv Fed Ceara, Dept Clin Med, HEMOCE, BR-60435160 Fortaleza, Ceara, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Res Lab, BR-04023062 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent243-247
dc.identifierhttp://dx.doi.org/10.1093/tropej/fmm113
dc.identifier.citationJournal of Tropical Pediatrics. Oxford: Oxford Univ Press, v. 54, n. 4, p. 243-247, 2008.
dc.identifier.doi10.1093/tropej/fmm113
dc.identifier.issn0142-6338
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30834
dc.identifier.wosWOS:000257965100006
dc.language.isoeng
dc.publisherOxford Univ Press
dc.relation.ispartofJournal of Tropical Pediatrics
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.oxfordjournals.org/access_purchase/self-archiving_policyb.html
dc.subjectiron deficiency anemiaen
dc.subjectpreschoolen
dc.subjectfortified foodsen
dc.subjectironen
dc.subjecthemoglobinen
dc.titleAnemia reduction in preschool children with the addition of low doses of iron to school mealsen
dc.typeinfo:eu-repo/semantics/article
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