Dental Implants Installed in Irradiated Jaws: A Systematic Review

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dc.contributor.authorChambrone, L.
dc.contributor.authorMandia, J. [UNIFESP]
dc.contributor.authorShibli, J. A.
dc.contributor.authorRomito, G. A.
dc.contributor.authorAbrahao, M. [UNIFESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Guarulhos
dc.date.accessioned2016-01-24T14:34:50Z
dc.date.available2016-01-24T14:34:50Z
dc.date.issued2013-12-01
dc.description.abstractThe aim of this study was to assess the survival rate of titanium implants placed in irradiated jaws. MEDLINE, EMBASE, and CENTRAL were searched for studies assessing implants that had been placed in nongrafted sites of irradiated patients. Random effects meta-analyses assessed implant loss in irradiated versus nonirradiated patients and in irradiated patients treated with hyperbaric oxygen (HBO) therapy. of 1,051 potentially eligible publications, 15 were included. A total of 10,150 implants were assessed in the included studies, and of these, 1,689 (14.3%) had been placed in irradiated jaws. the mean survival rate in the studies ranged from 46.3% to 98.0%. the pooled estimates indicated a significant increase in the risk of implant failure in irradiated patients (risk ratio: 2.74; 95% confidence interval: 1.86, 4.05; p < .00001) and in maxillary sites (risk ratio: 5.96; 95% confidence interval: 2.71, 13.12; p < .00001). Conversely, HBO therapy did not reduce the risk of implant failure (risk ratio: 1.28; 95% confidence interval: 0.19, 8.82; p = .80). Radiotherapy was linked to higher implant failure in the maxilla, and HBO therapy did not improve implant survival. Most included publications reported data on machined implants, and only 3 studies on HBO therapy were included. Overall, implant therapy appears to be a viable treatment option for reestablishing adequate occlusion and masticatory conditions in irradiated patients.en
dc.description.affiliationUniv São Paulo, Sch Dent, Dept Stomatol, Div Periodont, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Otorhinolaryngol & Head & Neck Surg, São Paulo, Brazil
dc.description.affiliationUniv Guarulhos, Dent Res Div, Dept Periodontol & Oral Implantol, São Paulo, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Otorhinolaryngol & Head & Neck Surg, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent119S-130S
dc.identifierhttp://dx.doi.org/10.1177/0022034513504947
dc.identifier.citationJournal of Dental Research. Thousand Oaks: Sage Publications Inc, v. 92, n. S12, p. 119S-130S, 2013.
dc.identifier.doi10.1177/0022034513504947
dc.identifier.issn0022-0345
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37067
dc.identifier.wosWOS:000329542600003
dc.language.isoeng
dc.publisherSage Publications Inc
dc.relation.ispartofJournal of Dental Research
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.uk.sagepub.com/aboutus/openaccess.htm
dc.subjectradiotherapyen
dc.subjectosseointegrationen
dc.subjectprognosisen
dc.subjectcranial irradiationen
dc.subjectdental implantationen
dc.subjectendosseousen
dc.subjectmeta-analysisen
dc.titleDental Implants Installed in Irradiated Jaws: A Systematic Reviewen
dc.typeinfo:eu-repo/semantics/article
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