Tretinoin peel: a critical view

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dc.citation.issue3
dc.citation.volume92
dc.contributor.authorSumita, Juliana Mayumi
dc.contributor.authorLeonardi, Gislaine Ricci
dc.contributor.authorBagatin, Edileia
dc.coverageRio De Janeiro Rj
dc.date.accessioned2020-07-13T11:53:17Z
dc.date.available2020-07-13T11:53:17Z
dc.date.issued2017
dc.description.abstractThe tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and nonmelanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen ( interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary.en
dc.description.affiliationUniv Fed Sao Paulo UNIFESP, Unit Cosmiatry Surg & Oncol, Dept Dermatol, Paulista Med Sch, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM UNIFESP, Paulista Med Sch, Dept Dermatol, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Estadual Campinas Unicamp, Sch Pharmaceut Sci, Campinas, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo UNIFESP, Unit Cosmiatry Surg & Oncol, Dept Dermatol, Paulista Med Sch, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM UNIFESP, Paulista Med Sch, Dept Dermatol, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent363-366
dc.identifierhttp://dx.doi.org/10.1590/abd1806-4841.201755325
dc.identifier.citationAnais Brasileiros De Dermatologia. Rio De Janeiro Rj, v. 92, n. 3, p. 363-366, 2017.
dc.identifier.doi10.1590/abd1806-4841.201755325
dc.identifier.fileS0365-05962017000300363.pdf
dc.identifier.issn0365-0596
dc.identifier.scieloS0365-05962017000300363
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/54511
dc.identifier.wosWOS:000406304900011
dc.language.isoeng
dc.publisherSoc Brasileira Dermatologia
dc.relation.ispartofAnais Brasileiros De Dermatologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChemexfoliationen
dc.subjectKeratosisen
dc.subjectactinicen
dc.subjectMelanosisen
dc.subjectSkin agingen
dc.subjectTretinoinen
dc.titleTretinoin peel: a critical viewen
dc.typeinfo:eu-repo/semantics/article
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