Guidelines for the management and treatment of periodic fever syndromes familial mediterranean fever

Página do item simplificado
dc.contributor.authorTerreri, Maria Teresa R. A. [UNIFESP]
dc.contributor.authorBernardo, Wanderley Marques
dc.contributor.authorLen, Claudio Arnaldo [UNIFESP]
dc.contributor.authorAlmeida da Silva, Clovis Artur
dc.contributor.authorRibeiro de Magalhaes, Cristina Medeiros
dc.contributor.authorSacchetti, Silvana B.
dc.contributor.authorLeme Ferriani, Virginia Paes
dc.contributor.authorPetry Piotto, Daniela Gerent [UNIFESP]
dc.contributor.authorCavalcanti, Andre de Souza
dc.contributor.authorde Moraes, Ana Julia Pantoja
dc.contributor.authorSztajnbok, Flavio Roberto
dc.contributor.authorFeitosa de Oliveira, Sheila Knupp
dc.contributor.authorArruda Campos, Lucia Maria
dc.contributor.authorBandeira, Marcia
dc.contributor.authorSena Teixeira Santos, Flavia Patricia
dc.contributor.authorMagalhaes, Claudia Saad
dc.date.accessioned2019-01-21T10:30:00Z
dc.date.available2019-01-21T10:30:00Z
dc.date.issued2016
dc.description.abstractObjective: To establish guidelines based on scientific evidence for the management of familial Mediterranean fever. Description of the evidence collection method: The Guideline was prepared from 5 clinical questions that were structured through PICO (Patient, Intervention or indicator, Comparison and Outcome), to search in key primary scientific information databases. After defining the potential studies to support the recommendations, these were graduated considering their strength of evidence and grade of recommendation. Results: 10,341 articles were retrieved and evaluated by title and abstracten
dc.description.abstractfrom these, 46 articles were selected to support the recommendations. Recommendations: 1. The diagnosis of FMF is based on clinical manifestations, characterized by recurrent febrile episodes associated with abdominal pain, chest or arthritis of large jointsen
dc.description.abstract2. FMF is a genetic disease presenting an autosomal recessive trait, caused by mutation in the MEFV geneen
dc.description.abstract3. Laboratory tests are not specific, demonstrating high serum levels of inflammatory proteins in the acute phase of the disease, but also often showing high levels even between attacks. SAA serum levels may be especially useful in monitoring the effectiveness of treatmenten
dc.description.abstract4. The therapy of choice is colchicineen
dc.description.abstractthis drug has proven effectiveness in preventing acute inflammatory episodes and progression towards amyloidosis in adultsen
dc.description.abstract5. Based on the available information, the use of biological drugs appears to be an alternative for patients with FMF who do not respond or are intolerant to therapy with colchicine. (C) 2015 Elsevier Editora Ltda. All rights reserved.en
dc.description.affiliationSetor de Reumatologia Pediátrica, Departamento de Pediatria, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.affiliationCentro de Desenvolvimento de Educação Médica, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brasil
dc.description.affiliationUnidade de Reumatologia Pediátrica, Instituto da Criança, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brasil
dc.description.affiliationHospital da Criança de Brasília José Alencar (HCB), Brasília, DF, Brasil
dc.description.affiliationIrmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil
dc.description.affiliationServiço de Imunologia, Alergia e Reumatologia Pediátrica, Departamento de Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto, SP, Brasil
dc.description.affiliationServiço de Reumatologia, Hospital das Clínicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil
dc.description.affiliationUniversidade Federal do Pará (UFPA), Belém, PA, Brasil
dc.description.affiliationServiço de Reumatologia, Núcleo de Estudos da Saúde do Adolescente, Universidade do Estado do Rio de Janeiro (Uerj), Rio de Janeiro, RJ, Brasil
dc.description.affiliationInstituto de Puericultura e Pediatria Martagão Gesteira, Serviço de Reumatologia Pediátrica, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brasil
dc.description.affiliationHospital Pequeno Príncipe, Curitiba, PR, Brasil
dc.description.affiliationServiço de Reumatologia, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil
dc.description.affiliationUnidade de Reumatologia Pediátrica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp), Botucatu, SP, Brasil
dc.description.affiliationUnifespSetor de Reumatologia Pediátrica, Departamento de Pediatria, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil
dc.description.sourceWeb of Science
dc.format.extent37-43
dc.identifierhttp://dx.doi.org/10.1016/j.rbr.2015.08.006
dc.identifier.citationRevista Brasileira De Reumatologia. New york, v. 56, n. 1, p. 37-43, 2016.
dc.identifier.doi10.1016/j.rbr.2015.08.006
dc.identifier.fileS0482-50042016000100037.pdf
dc.identifier.issn0482-5004
dc.identifier.scieloS0482-50042016000100037
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/49530
dc.identifier.wosWOS:000374895300007
dc.language.isopor
dc.publisherElsevier science inc
dc.relation.ispartofRevista Brasileira De Reumatologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFamilial Mediterranean Feveren
dc.subjectGuidelinesen
dc.subjectChildhooden
dc.subjectFeveren
dc.subjectAutoinflammatory SyndromesAutoinflammatory Syndromesen
dc.subjectColchicine Therapyen
dc.subjectAmyloidosisen
dc.subjectActivationen
dc.subjectGenotypeen
dc.subjectPatienten
dc.subjectAttacksen
dc.subjectTransplantationen
dc.subjectInterleukin-1en
dc.subjectCanakinumaben
dc.titleGuidelines for the management and treatment of periodic fever syndromes familial mediterranean feveren
dc.titleDiretrizes de conduta e tratamento de síndromes febris periódicas associadas a febre familiar do Mediterrâneopt
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos