The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis

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dc.contributor.authorAndreatini, R.
dc.contributor.authorBlanchard, C.
dc.contributor.authorBlanchard, R.
dc.contributor.authorBrandão, M.l.
dc.contributor.authorCarobrez, A.p.
dc.contributor.authorGriebel, G.
dc.contributor.authorGuimarães, F.s.
dc.contributor.authorHandley, S.l.
dc.contributor.authorJenck, F.
dc.contributor.authorLeite, Jose Roberto [UNIFESP]
dc.contributor.authorRodgers, J.
dc.contributor.authorSchenberg, L.c.
dc.contributor.authorDa Cunha, C.
dc.contributor.authorGraeff, F.g.
dc.contributor.institutionUniversidade Federal do Paraná Departamento de Farmacologia Laboratório de Fisiologia e Farmacologia do Sistema Nervoso Central
dc.contributor.institutionUniversity of Hawaii Department of Neurobiology
dc.contributor.institutionUniversity of Hawaii Department of Psychology
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de Santa Catarina Departamento de Farmacologia
dc.contributor.institutionCentral Nervous System Research Department Sanofi Synthelabo
dc.contributor.institutionAston University Institute of Pharmaceutical Sciences
dc.contributor.institutionHoffmann-La Roche Ltd.
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversity of Leeds Department of Psychology Ethopharmacology Laboratory
dc.contributor.institutionUniversidade Federal do Espírito Santo Centro de Biomedicina Departamento de Ciências Fisiológicas
dc.date.accessioned2015-06-14T13:25:10Z
dc.date.available2015-06-14T13:25:10Z
dc.date.issued2001-02-01
dc.description.abstractThis article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.en
dc.description.affiliationUniversidade Federal do Paraná Departamento de Farmacologia Laboratório de Fisiologia e Farmacologia do Sistema Nervoso Central
dc.description.affiliationUniversity of Hawaii Department of Neurobiology
dc.description.affiliationUniversity of Hawaii Department of Psychology
dc.description.affiliationUniversidade de São Paulo Faculdade de Filosofia Ciências e Letras de Ribeirão Preto Departamento de Psicobiologia
dc.description.affiliationUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto Departamento de Fisiologia
dc.description.affiliationUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto Departamento de Neuropsiquiatria
dc.description.affiliationUniversidade Federal de Santa Catarina Departamento de Farmacologia
dc.description.affiliationCentral Nervous System Research Department Sanofi Synthelabo
dc.description.affiliationAston University Institute of Pharmaceutical Sciences
dc.description.affiliationHoffmann-La Roche Ltd.
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Psicologia
dc.description.affiliationUniversity of Leeds Department of Psychology Ethopharmacology Laboratory
dc.description.affiliationUniversidade Federal do Espírito Santo Centro de Biomedicina Departamento de Ciências Fisiológicas
dc.description.affiliationUnifespUNIFESP, EPM, Depto. de Psicologia
dc.description.sourceSciELO
dc.format.extent145-154
dc.identifierhttp://dx.doi.org/10.1590/S0100-879X2001000200001
dc.identifier.citationBrazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 34, n. 2, p. 145-154, 2001.
dc.identifier.doi10.1590/S0100-879X2001000200001
dc.identifier.fileS0100-879X2001000200001.pdf
dc.identifier.issn0100-879X
dc.identifier.scieloS0100-879X2001000200001
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/1096
dc.identifier.wosWOS:000167337600001
dc.language.isoeng
dc.publisherAssociação Brasileira de Divulgação Científica
dc.relation.ispartofBrazilian Journal of Medical and Biological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectpanicen
dc.subjectanxietyen
dc.subjectfearen
dc.subjectanxiolyticsen
dc.subject5-HTen
dc.subjectbenzodiazepinesen
dc.subjectserotoninen
dc.subjectamygdalaen
dc.subjectperiaqueductal gray matteren
dc.subjectanimal modelsen
dc.titleThe brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basisen
dc.typeinfo:eu-repo/semantics/article
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