Tetanus and diphtheria antibodies and response to a booster dose in Brazilian HIV-1-infected women

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dc.contributor.authorBonetti, TCS
dc.contributor.authorSucci, RCM
dc.contributor.authorWeckx, L. Y.
dc.contributor.authorTavares-Lopes, L.
dc.contributor.authorMoraes-Pinto, M. I. de
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:37:22Z
dc.date.available2016-01-24T12:37:22Z
dc.date.issued2004-09-09
dc.description.abstractTetanus and diphtheria (Td) antibodies were studied in HIV-1-infected women during puerperium. HIV group (n = 61) was compared with Control group (n = 101). Twenty-one women from HIV and 13 from Control group who had antibody levels lower than 0.1 IU/mL received a booster with Td vaccine. Antibodies were assessed by double antigen ELISA. Mean tetanus and diphtheria antibody levels from HIV group were lower than those from Control group. Multiple linear regression analysis showed that tetanus and diphtheria antibody levels were decreased by HIV-1-infection, and that was independent of the reduction due to the time interval between last booster and antibody assessment. After a booster dose, both groups had an increase in mean tetanus and diphtheria antibody levels, but in Control group the levels were higher than in HIV group. (C) 2004 Elsevier B.V. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Div Pediat Infect Dis, Dept Pediat, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Pediat Infect Dis, Dept Pediat, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent3707-3712
dc.identifierhttp://dx.doi.org/10.1016/j.vaccine.2004.03.023
dc.identifier.citationVaccine. Oxford: Elsevier B.V., v. 22, n. 27-28, p. 3707-3712, 2004.
dc.identifier.doi10.1016/j.vaccine.2004.03.023
dc.identifier.issn0264-410X
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/27936
dc.identifier.wosWOS:000223815100020
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofVaccine
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjecttetanusen
dc.subjectdiphtheriaen
dc.subjectHIV infectionen
dc.titleTetanus and diphtheria antibodies and response to a booster dose in Brazilian HIV-1-infected womenen
dc.typeinfo:eu-repo/semantics/article
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