Diffusion-weighted magnetic resonance imaging indicates the severity of acute pancreatitis

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dc.contributor.authorTertulino, Franklin de Freitas [UNIFESP]
dc.contributor.authorSchraibman, Vladimir [UNIFESP]
dc.contributor.authorArdengh, Jose Celso [UNIFESP]
dc.contributor.authorEspirito-Santo, Danilo Cerqueira do [UNIFESP]
dc.contributor.authorAjzen, Sergio Aron [UNIFESP]
dc.contributor.authorApodaca Torrez, Franz Robert [UNIFESP]
dc.contributor.authorLobo, Edson Jose [UNIFESP]
dc.contributor.authorSzejnfeld, Jacob [UNIFESP]
dc.contributor.authorGoldman, Suzan Menasce [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2016-01-24T14:39:57Z
dc.date.available2016-01-24T14:39:57Z
dc.date.issued2015-02-01
dc.description.abstractPurpose: To test the use of diffusion-weighted magnetic resonance imaging (DW-MRI) to differentiate between different degrees of severity of acute pancreatitis (AP).Method: Thirty-six patients who underwent DW-MRI and magnetic resonance cholangiopancreatography were divided into patients with mild AP (mAP, n = 15), patients with necrotizing AP (nAP, n = 8), and patients with a normal pancreas (nP, n = 15; controls). the pancreas was divided into head, body, and tail, and each segment was classified according to image features: pattern 1, normal; pattern 2, mild inflammation; and pattern 3, necrosis. Apparent diffusion coefficients (ADCs) were measured in each segment and correlated with clinical diagnoses.Results: A total of 108 segments was assessed (three segments per patient). Segments classified as pattern 1 in the nP and mAP groups showed similar ADC values (P = 0.29). ADC values calculated for the pancreatic segments grouped according to the different image patterns (1-3) were significantly different (P < 0.001). Comparisons revealed significant differences in signal intensity between all three patterns (P < 0.05).Conclusions: DW-MRI was a compatible and safe image option to differentiate tissue image patterns in patients with mAP, nAP, and nP, mainly in those with contrain-dications to contrast-enhanced MRI (which is classically required for determining the presence of necrosis) or computed tomography. ADC measures allowed precise differentiation between patterns 1, 2, and 3.en
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Diagnost Imaging, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Surg, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Med Sch Ribeirao Preto, Div Surg & Anat, Ribeirao Preto, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Diagnost Imaging, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Surg, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent265-271
dc.identifierhttp://dx.doi.org/10.1007/s00261-014-0205-y
dc.identifier.citationAbdominal Imaging. New York: Springer, v. 40, n. 2, p. 265-271, 2015.
dc.identifier.doi10.1007/s00261-014-0205-y
dc.identifier.issn0942-8925
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38674
dc.identifier.wosWOS:000348298800006
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofAbdominal Imaging
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.subjectAcute necrotizing pancreatitisen
dc.subjectDiffusion magnetic resonance imagingen
dc.subjectDifferential diagnosisen
dc.titleDiffusion-weighted magnetic resonance imaging indicates the severity of acute pancreatitisen
dc.typeinfo:eu-repo/semantics/article
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