Legume vicilins (7S storage globulins) inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells

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dc.contributor.authorGomes, V. M.
dc.contributor.authorOkorokov, L. A.
dc.contributor.authorRose, T. L.
dc.contributor.authorFernandes, KVS
dc.contributor.authorXavier-Filho, J.
dc.contributor.institutionUniv Estadual Norte Fluminense
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Fed Ceara
dc.date.accessioned2016-01-24T12:30:32Z
dc.date.available2016-01-24T12:30:32Z
dc.date.issued1998-02-02
dc.description.abstractVicilin (7S storage proteins) isolated from different legume seeds were shown to inhibit yeast growth and glucose stimulated acidification of the medium by yeast cells. the degree of growth inhibition varied with the origin of vicilins. It was more than 90% for vicilins from cowpea (Vigna unguiculata, cultivar pitiuba) and equal to 65% for vicilins from Vigna radiata, in the case of Saccharomyces cerevisae. Vicilins from cowpea seeds inhibited the glucose stimulated acidification of the medium by S. cerevisae up to 60%. We have also observed that vicilins bind to yeast cells. We suggest that vicilins bind to chitin-containing structures of yeast cells and that such association could result in inhibition of H+ pumping, cell growth and spore formation. A final consequence of the yeast growth inhibition by vicilins is (probably) the formation of spores. (C) 1998 Elsevier Science B.V.en
dc.description.affiliationUniv Estadual Norte Fluminense, Ctr Biociencias & Biotecnol, Lab Quim & Funcao Prot & Peptideos, BR-28015620 Campos Dos Goytacazes, RJ, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Curso Pos Grad Biol Mol, São Paulo, Brazil
dc.description.affiliationUniv Fed Ceara, Dept Bioquim & Biol Mol, BR-60455760 Fortaleza, Ceara, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Curso Pos Grad Biol Mol, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent207-216
dc.identifierhttp://dx.doi.org/10.1016/S0304-4165(97)00100-1
dc.identifier.citationBiochimica Et Biophysica Acta-general Subjects. Amsterdam: Elsevier B.V., v. 1379, n. 2, p. 207-216, 1998.
dc.identifier.doi10.1016/S0304-4165(97)00100-1
dc.identifier.issn0304-4165
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/25865
dc.identifier.wosWOS:000072285000006
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBiochimica Et Biophysica Acta-general Subjects
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectvicilinen
dc.subject7S storage proteinen
dc.subjectlegume seeden
dc.subjectchitin-binding proteinen
dc.subjectH+ pumpingen
dc.subject(Saccharomyces cerevisae)en
dc.subject(Candida albicans)en
dc.subject(yeast)en
dc.titleLegume vicilins (7S storage globulins) inhibit yeast growth and glucose stimulated acidification of the medium by yeast cellsen
dc.typeinfo:eu-repo/semantics/article
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