Sialic acids in fungi: A minireview

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dc.contributor.authorAlviano, C. S.
dc.contributor.authorTravassos, L. R. [UNIFESP]
dc.contributor.authorSchauer, R.
dc.contributor.institutionUniv Kiel
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T12:30:52Z
dc.date.available2016-01-24T12:30:52Z
dc.date.issued1999-09-01
dc.description.abstractThe increasing number of reports on the presence of sialic acids in fungi (N-acetyl, N-glycolyl-and 5,9-N,O-diacetyl neuraminic acids) based on direct and indirect evidence warrants the present review. Formerly suggested as sialidase-sensitive sources of anionic groups at the cell surface of fungal species grown in chemically defined media (e.g., Fonsecaea pedrosoi), sialic acids have also been found in Sporothrix schenckii, Paracoccidioides brasiliensis, Cryptococcus neoformans and recently, in Candida albicans. Methods used involved adequate hydrolysis and extraction procedures, HTPLC, gas-chromatography, colorimetry, mass spectroscopy, sialidase-sensitive lectin and influenza virus binding. Apart from protecting fungal cells against phagocytosis (S. schenckii, C. neoformans) and playing a cellular structural role (F. pedrosoi), other biological functions of sialic acids are still being investigated.en
dc.description.affiliationUniv Kiel, Inst Biochem, D-24098 Kiel, Germany
dc.description.affiliationUniv Fed Rio de Janeiro, Inst Microbiol Prof Paulo de Goes, Rio de Janeiro, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Disciplina Biol Celular, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Disciplina Biol Celular, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent545-554
dc.identifierhttp://dx.doi.org/10.1023/A:1007078106280
dc.identifier.citationGlycoconjugate Journal. Dordrecht: Kluwer Academic Publ, v. 16, n. 9, p. 545-554, 1999.
dc.identifier.doi10.1023/A:1007078106280
dc.identifier.issn0282-0080
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/26138
dc.identifier.wosWOS:000085542100008
dc.language.isoeng
dc.publisherKluwer Academic Publ
dc.relation.ispartofGlycoconjugate Journal
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectfungien
dc.subjectsialic acidsen
dc.subjectanionic groupsen
dc.subjectN-acetylneuraminic aciden
dc.subjectO-acetylated sialic acidsen
dc.subjectfungal pathogenesisen
dc.titleSialic acids in fungi: A minireviewen
dc.typeinfo:eu-repo/semantics/article
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