Depth of glandular crypts and its involvement in squamous intraepithelial cervical neoplasia submitted to large loop excision of transformation zone (LLETZ)

dc.contributor.authorOkazaki, C. [UNIFESP]
dc.contributor.authorFocchi, Gustavo Rubino de Azevedo [UNIFESP]
dc.contributor.authorTaha, Nabiha Saadi Abrahão [UNIFESP]
dc.contributor.authorAhmeida, P. Q. [UNIFESP]
dc.contributor.authorSchimidt, M. A. [UNIFESP]
dc.contributor.authorSpeck, Neila Maria de Góis [UNIFESP]
dc.contributor.authorRibalta, Julisa Chamorro Lascasas [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-15T17:22:27Z
dc.date.available2018-06-15T17:22:27Z
dc.date.issued2013-01-01
dc.description.abstractBackground: The authors aimed to confirm the depth of six mm in order to achieve an optimal eradication of the lesion. Materials and Methods: This is a retrospective observational study of 94 cervical surgical pieces from women aged 17 to 22 years with a cytocolpo-histopathological diagnosis of high-grade squamous cervical intraepithelial neoplasia (CIN II and/or CIN III) submitted to large loop excision of transformation zone (LLETZ). The glandular crypts and margins, both exposed or not to CIN, were assessed. The compromise and the maximum depth of the glandular crypts were noticed. Results: After LLETZ, 23 (24.47%) cases presented a neoplasic impairment of endocervical margin and ten (10.64%) of the ectocervical margin. The largest noticed crypt measured 4.500 mm and the shortest 0.100 mm, with an average of 2.148 mm.-Conclusions: Squamous CIN more frequently show the exposure of surgical margins to LLETZ. The deeper location of glandular crypts in the cases studied was 4.500 mm, while the largest neoplastic extension was 3.000 mm The therapeutic method depends on this knowledge.en
dc.description.affiliationUniv Fed Sao Paulo, UNIFESP, Escola Paulista Med EPM,Gynaecol Dept, Gynaecol Dis Prevent Ctr,Gen Gynaecol Discipline, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, UNIFESP, Escola Paulista Med EPM,Gynaecol Dept, Gynaecol Dis Prevent Ctr,Gen Gynaecol Discipline, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent48-50
dc.identifierhttp://www.irog.net/download/?magazine=108
dc.identifier.citationEuropean Journal Of Gynaecological Oncology. Montreal: I R O G Canada, Inc, v. 34, n. 1, p. 48-50, 2013.
dc.identifier.issn0392-2936
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/43608
dc.identifier.wosWOS:000314617700008
dc.language.isoeng
dc.publisherI R O G Canada, Inc
dc.relation.ispartofEuropean Journal Of Gynaecological Oncology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGlandular crypten
dc.subjectCervical intraepithelial neoplasiaen
dc.subjectLLETZen
dc.subjectCervixen
dc.titleDepth of glandular crypts and its involvement in squamous intraepithelial cervical neoplasia submitted to large loop excision of transformation zone (LLETZ)en
dc.typeinfo:eu-repo/semantics/article
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