Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

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dc.citation.volume28
dc.contributor.authorGiraldes, Ana Laura Albertoni [UNIFESP]
dc.contributor.authorSousa, Angela Maria
dc.contributor.authorSlullitel, Alexandre
dc.contributor.authorGuimaraes, Gabriel Magalhaes Nunes
dc.contributor.authorSantos, Melina Genevieve Mary Egan
dc.contributor.authorPinto, Renata Evangelista
dc.contributor.authorAshmawi, Hazem Adel
dc.contributor.authorSakata, Rioko Kimiko [UNIFESP]
dc.coverageNew York
dc.date.accessioned2020-10-30T18:46:30Z
dc.date.available2020-10-30T18:46:30Z
dc.date.issued2016
dc.description.abstractStudy Objective: The purpose of this trial was to assess if tramadol wound infiltration is superior to intravenous (IV) tramadol after minor surgical procedures in children because tramadol seems to have local anesthetic like effect. Design: Randomized double-blind controlled trial. Setting: Postanesthesia care unit. Patients: Forty children, American Society of Anesthesiologists physical status I or II, scheduled to elective inguinal hernia repair. Interventions: Children were randomly distributed in 1 of 2 groups: IV tramadol (group 1) or subcutaneous infiltration with tramadol (group 2). At the end of the surgery, group 1 received 2 mg/kg tramadol (3 mL) by IV route and 3-mL saline into the surgical wound; group 2 received 2 mg/kg tramadol (3 mL) into the surgical wound and 3-mL saline by IV route. Measurements: In the postanesthesia care unit, patients were evaluated for pain intensity, nausea and vomiting, time to first rescue medication, and total rescue morphine and dipyrone consumption. Main Results: Pain scores measured during the postanesthesia recovery time were similar between groups. Time to first rescue medication was shorter, but not statistically significant in the IV group. The total dose of rescue morphine and dipyrone was also similar between groups. Conclusions: We concluded that tramadol was effective in reducing postoperative pain in children, and there was no difference in pain intensity, nausea and vomiting, or somnolence regarding IV route or wound infiltration. (C) 2016 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniv Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
dc.description.affiliationCanc Inst State Sao Paulo, Pain Management Serv, Sao Paulo, Brazil
dc.description.affiliationSanta Paula Hosp, Dept Anesthesia & Pain Management, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Univ Hosp, Dept Anesthesia, Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Hosp Clin, Dept Anesthesia, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent62-66
dc.identifierhttps://doi.org/10.1016/j.jclinane.2015.08.009
dc.identifier.citationJournal Of Clinical Anesthesia. New York, v. 28, p. 62-66, 2016.
dc.identifier.doi10.1016/j.jclinane.2015.08.009
dc.identifier.issn0952-8180
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/58493
dc.identifier.wosWOS:000369194300013
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofJournal Of Clinical Anesthesia
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectInfiltration anesthesiaen
dc.subjectTramadolen
dc.subjectIntravenous administrationen
dc.subjectPostoperative painen
dc.subjectHemioplastyen
dc.titleTramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trialen
dc.typeinfo:eu-repo/semantics/article
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