Osteoporosis after solid organ transplantation

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dc.contributor.authorKulak, Carolina Aguiar Moreira
dc.contributor.authorBorba, Victoria Zeghbi Cochenski|Kulak Junior, Jaime
dc.contributor.authorCustodio, Melani Ribeiro [UNIFESP]
dc.contributor.institutionUniv Fed Parana
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2018-06-18T11:04:06Z
dc.date.available2018-06-18T11:04:06Z
dc.date.issued2012-09-01
dc.description.abstractOsteoporosis and high risk of fractures have emerged as frequent and devastating complications of organ solid transplantation process. Bone loss after organ transplant is related to adverse effects of immunosuppressive drugs on bone remodeling and bone quality. Many factors contribute to the pathogenesis of osteoporosis in transplanted patients. This review address the mechanisms of bone loss that occurs both in the early and late post-transplant periods including the contribution of the immunosuppressive agents as well as the specific features to bone loss after kidney, lung, liver and cardiac transplantation. Therapy for bone loss and prevention of fragility fracture in the transplant recipient will also be discussed.en
dc.description.affiliationUniv Fed Parana, Dept Internal Med, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUniv Fed Parana, Div Endocrinol SEMPR, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUniv Fed Parana, Dept Obstet & Gynecol, BR-80060000 Curitiba, Parana, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Internal Med, Div Nephrol, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Internal Med, Div Nephrol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent221-231
dc.identifierhttp://www.minervamedica.it/it/riviste/minerva-endocrinologica/articolo.php?cod=R07Y2012N03A0221
dc.identifier.citationMinerva Endocrinologica. Turin: Edizioni Minerva Medica, v. 37, n. 3, p. 221-231, 2012.
dc.identifier.issn0391-1977
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/44908
dc.identifier.wosWOS:000308788200002
dc.language.isoeng
dc.publisherEdizioni Minerva Medica
dc.relation.ispartofMinerva Endocrinologica
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectOsteoporosisen
dc.subjectImmunosuppressive agentsen
dc.subjectFractures, boneen
dc.titleOsteoporosis after solid organ transplantationen
dc.typeinfo:eu-repo/semantics/article
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