Navegando por Palavras-chave "Binge eating"

Agora exibindo 1 - 6 de 6
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Eating disorders in adolescents: Correlations between symptoms and central control of eating behavior
    (Elsevier B.V., 2011-01-01) Lofrano-Prado, Mara Cristina [UNIFESP]; Prado, Wagner Luiz do; Piano, Aline de [UNIFESP]; Tock, Lian [UNIFESP]; Caranti, Danielle Arisa [UNIFESP]; Nascimento, Claudia Maria da Penha Oller do [UNIFESP]; Oyama, Lila Missae [UNIFESP]; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Dâmaso, Ana Raimunda [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Univ Pernambuco
    The aim of this study was to verify the relationship between eating disorders (binge eating and bulimia nervosa) and body image dissatisfaction with BMI, anorexigenic and orexigenic factors in adolescents. Thirty-two adolescents, (13 obese [BMI = 36.65 +/- 5.68] and 19 non-obese [BMI = 22.18 +/- 3.11]), aged between 14 and 19 y, were recruited. Symptoms of eating disorders were measured by self-report questionnaires (BSQ BITE and BES). Hormones, cytokines and neuropeptides were determined by Elisa kits (Phoenix peptide). A positive correlation was found between: leptin and BES (r = .724), BSQ(r = .705) and BITE (r = .696); BMI and BES (r = .663), BSQ (r = .525) and BITE (r = .732); the same pattern was observed to insulin and TNF-alpha. A negative correlation was found in alpha-MSH and AgRP with BES, BSQ and BITE. Blood levels of hormones and neuropeptides could be the link between obesity and eating disorders in adolescents. However, it is not clear which is the cause and which is the consequence. (C) 2010 Elsevier B.V. All rights reserved.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Efeito da terapia interdisciplinar no consumo de alimentos palatáveis e nos sintomas de transtorno de compulsão alimentar periódica em indivíduos obesos
    (Universidade Federal de São Paulo (UNIFESP), 2016-08-26) Leite, Paula Bresciani [UNIFESP]; Oliveira, Camila Aparecida Machado de [UNIFESP]; http://lattes.cnpq.br/4886067148875464; http://lattes.cnpq.br/1124406576194567; Universidade Federal de São Paulo (UNIFESP)
    Introduction: Obesity prevalence has risen steadily in most industrialized and developed countries and a major determinant of this pandemic relates to excessive food intake. The palatability of food can be an important predictor of intake, since it is closely related to activation of the reward system in the central nervous system. The higher activity of this reward circuit may contribute to excessive consumption and hence to increased weight, binge eating disorder (BED) symptoms and obesity. Due to the multifactorial etiology of obesity, it is believed that a long term interdisciplinary treatment focused on lifestyle changes, be the most effective strategy for its control. Objective: To evaluate the effect of interdisciplinary therapy on the consumption of palatable food and the symptoms of binge eating in obese. Methods: Forty-seven (47) subjects completed the long-term therapy consisting of nutritionists, psychologists, physical trainers and physiotherapists. Lipid and glucose profile and the perimeters (hip, abdomen, neck), body mass index (BMI) and body mass were evaluated. Symptoms of BED were assessed by Binge Eating Scale (BES). Dietary intake was assessed by the semi-quantitative Food Frequency Questionnaire (FFQ). Results: After the intervention there was a reduction of anthropometric variables and increased HDL-c, both significant (p < 0.001). BES score reduced. Before intervention 18% of subjects were classified as moderate bingers and 9% as severe bingers. After therapy all subjects were classified as without binge eating symptoms. There was a significant reduction in the consumption of palatable foods after therapy (p < 0.001). Strong correlations among symptoms of binge eating and anthropometric and serum variables and frequency of consumption of palatable foods weren?t observed (p> 0.05). Neither were found significant correlation among consumption of palatable food and anthropometric and serum variables (P > 0.05). Conclusion: The therapy is effective in reducing the consumption of palatable food and the prevalence of BED, highlighting the importance of this approach.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Long-term interdisciplinary therapy decreases symptoms of binge eating disorder and prevalence of metabolic syndrome in adults with obesity
    (Pergamon-Elsevier Science Ltd, 2017) Leite, Paula Bresciani [UNIFESP]; Dâmaso, Ana Raimunda [UNIFESP]; Poli, Vanessa Fadanelli Schoenardie [UNIFESP]; Sanches, Ricardo Badan; Andrade-Silva, Stephan Garcia [UNIFESP]; Fidalgo, João Pedro Novo [UNIFESP]; Nascimento, Maythe Amaral [UNIFESP]; Oliveira, Camila Aparecida Machado de [UNIFESP]; Caranti, Danielle Arisa [UNIFESP]
    Obesity-associated comorbidities greatly impact the quality and expectancy of life. Binge eating disorder (BED) is the most prevalent eating disorder and it is an important risk factor for obesity and metabolic syndrome (MetS). For these reasons, we aimed to assess the effect of an interdisciplinary therapy on the symptoms of BED and the prevalence of MetS in obese adults. It was hypothesized that the interdisciplinary therapy would decrease symptoms of BED and markers of MetS. Twenty-four volunteers (BMI 34.80 ± 3.17 kg/m2; 41.21 ± 6.28 years old) completed a 32-week intervention. Biochemical characteristics, body composition, the degree of symptoms of binge eating, and macronutrients, and sodium consumption pre- and post-treatment were determined. The prevalence of MetS dropped from 75% to 45.8%, post-therapy. Among the markers of MetS, waist circumference and systolic blood pressure decreased significantly, whereas high-density lipoprotein levels increased. Fasting plasma glucose, diastolic blood pressure, and triglycerides did not change. Based on binge-eating scale (BES) scores, before therapy, 33.3% of volunteers were classified as moderate bingers, and after therapy all volunteers were classified as having no BED symptoms. No difference in the prevalence of MetS between individuals classified as normal or moderate bingers was observed, but we found a positive post-therapy correlation between the BES score and body fat, gynoid fat and trunk fat. Sodium, fat, and carbohydrate consumption decreased. Protein intake did not change. In conclusion, the interdisciplinary approach was efficient in reducing symptoms of BED and MetS prevalence in this population.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Relação entre sintomas depressão e marcadores inflamatórios em adolescentes obesos integrantes de um programa de tratamento interdisciplinar para mudança do estilo de vida
    (Universidade Federal de São Paulo (UNIFESP), 2016-07-08) Ferreira, Joana Pereira de Carvalho [UNIFESP]; Dâmaso, Ana Raimunda [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Obesity is a chronic disease which have multifactorial etiology and consequences, including altered humor states. Due to its high mobidity and mortality, several studies aims to investigate the associations between overweight and related diseases, targering decrese risks and identifie better control and treatment methods. It was observed that researches investigating the associations between obesity – and its inflammatory state –, with depression and anxiety showed contraditory results, indicating the need of more studies on the field. Thus, the present investigation aimed to evaluate the assocation between obesity and psychological symptoms, investigating more specifically the role of inflammatory markers on this relationships. Data collection were done for the Obesity Study Group, which performs a long-term interdisciplinary weight loss therapy with obese adolescents. The first study of this thesis investigated the associations between the changes on leptin concentrations and changes o depressive symptoms after long-term interdisciplinary weight loss therapy. It ws evaluated 75 obese adolescents (30 boys and 45 girls; 16.28 ± 2.37 years; BMI 35.75 ± 4.64 kg/m2), at baseline and after 01 year. Results showed a significant improvement on inflammatory profile related to obesity ando n depressive symptoms. Multiple regression analysis were performed to test the associations between the cited results, which showed that decreased leptin (mitigation of pro-inflammatory state) was a predictor of depressive symptoms amelioration, independente of changes in visceral fat (β=0.386; p= 0.002), body mass (β=0.226; p=0.05) and fat mass (β=0.308; p=0.009). These results were mor significante for girls than boys. The second study investigated the relationship between inflammatory markers and anxiety symptoms in obese with and without binge eating. It was included 80 adolescents (37 boys and 43 girls, 16.45 ± 2.35 years; BMI 36.33 ±4.88 kg/m2). Results demonstrated a significant weight loss, improvement on the body composition and inflammatory profile and a better psychological profile after therapy. Moreover, the leptin/adiponectin ratio was found as a predictor of decreased anxiety trait symptoms on the binge eating group, independent of gender (β=0.50; p=0.01), age (β=0.54; p=0.01), body mass (β=0.49; p=0.01), BMI (β=0.51; p=0.01), fat mass (β=0.56; p<0.01) and visceral fat (β=0.53; p<0.01). In conclusion, this thesis results demonstrated that inflammatory markers are associated with comorbid psychological symptoms (depression, anxiet and binge eating) in obese adolescentes.These results should be taken in account for the control and treatment of obesity and related psychological disorders.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Relações entre a resistência à insulina e a compulsão alimentar na obesidade
    (Universidade Federal de São Paulo (UNIFESP), 2018-12-05) Affonso, Luiz Henrique Lima [UNIFESP]; Gomes, Ricardo José [UNIFESP]; http://lattes.cnpq.br/2738281530091229; http://lattes.cnpq.br/6535934554509593; Universidade Federal de São Paulo (UNIFESP)
    Em alguns países a incidência de obesidade já é um problema de saúde público, na qual esta é acompanhada de diversas comorbidades que aumentam o risco de doenças cardiovasculares. Dentre as doenças que podem acompanhar a obesidade, a compulsão alimentar (CA) é uma que merece destaque. Um episódio de compulsão alimentar é um evento agudo caracterizado pela sensação de perda de controle sobre a ingestão alimentar, e ingestão de alimentos muito maior que uma pessoa semelhante e em situações semelhantes comeria, dentro de um período de 2 horas, e sem que haja os comportamentos compensatórios presentes na bulimia nervosa. A cronicidade deste comportamento de CA é critério de diagnóstico para o transtorno de compulsão alimentar (TCA), descrito no Manual Diagnóstico e Estatístico de Doenças Mentais (DSM) em sua quinta versão. O objetivo deste trabalho foi investigar a incidência de CA em pessoas com obesidade que passaram pelo grupo de estudo de obesidade (GEO) nos anos de 2012 a 2015 e 2017, e correlacionar CA com a resistência á insulina, analisada através do índice TyG (um índice de resistência a insulina computado através dos triglicerídeos e da glicose) nesta população. Foi encontrada incidência de 37,4% de comportamentos de CA na amostra de 238 obesos de ambos os sexos, sendo que das 195 mulheres 37,9% foram classificadas com compulsão alimentar, assim como 34,9% dos homens, não mostrando diferenças na incidência deste comportamento entre os homens e as mulheres. Ao analisar a CA e o índice TyG através de correlações (Spearman), não foi encontrado qualquer correlação entre esses dois fatores, sendo que mesmo quando estes critérios foram isolados para o sexo, não houve significância. Dados estes que ainda são controversos na literatura, que apresenta trabalhos que correlacionam ou não a resistência à insulina (normalmente pelo índice HOMA-IR) com comportamentos de CA ou TCA. Para concluir, o índice TyG é uma ferramenta barata e mais acessível que o índice HOMA-IR, para avaliação da resistência insulínica em pessoas com obesidade; o trabalho confirmou o já presente na literatura, de maior prevalência de CA em pessoas com obesidade do que naquelas sem. Os comportamentos de CA não apresentaram correlação ao índice TyG, no qual, estes comportamentos devam mostrar correlação com outros comportamentos psicopatológicos, como a ansiedade e a depressão.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Repetitive transcranial magnetic stimulation reduces cortisol concentrations in bulimic disorders
    (Cambridge Univ Press, 2011-06-01) Claudino, A. M. [UNIFESP]; Van den Eynde, F.; Stahl, D.; Dew, T.; Andiappan, M.; Kalthoff, J.; Schmidt, U.; Campbell, I. C.; Kings Coll London; Universidade Federal de São Paulo (UNIFESP); Kings Coll NHS Trust
    Background. in people with bulimic eating disorders, exposure to high-calorie foods can result in increases in food craving, raised subjective stress and salivary cortisol concentrations. This cue-induced food craving can be reduced by repetitive transcranial magnetic stimulation (rTMS). We investigated whether rTMS has a similar effect on salivary cortisol concentrations, a measure of hypothalamic-pituitary-adrenal axis (HPAA) activity.Method. We enrolled twenty-two female participants who took part in a double-blind randomized sham-controlled trial on the effects of rTMS on food craving. Per group, eleven participants were randomized to the real or sham rTMS condition. the intervention consisted of one session of high-frequency rTMS delivered to the left dorsolateral prefrontal cortex (DLPFC). Salivary cortisol concentrations were assessed at four time points throughout the 90-min trial. To investigate differences in post-rTMS concentrations between the real and sham rTMS groups, a random-effects model including the pre-rTMS cortisol concentrations as covariates was used.Results. Salivary cortisol concentrations following real rTMS were significantly lower compared with those following sham rTMS. in this sample, there was also a trend for real rTMS to reduce food craving more than sham rTMS.Conclusions. These results suggest that rTMS applied to the left DLPFC alters HPAA activity in people with a bulimic disorder.