Navegando por Palavras-chave "Eye Drops"
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- ItemAcesso aberto (Open Access)Idealização, desenvolvimento e testes de capas para auxiliar na identificação de frascos de colírios(Universidade Federal de São Paulo (UNIFESP), 2021) Costa, Ana Luiza Fontes De Azevedo [UNIFESP]; Schor, Paulo [UNIFESP]; Universidade Federal de São PauloPurpose: To describe the process of idealizing, developing and testing the acceptance and effectiveness of a prototype of sleeves to help identify eye drop bottles, reduce the risk of misidentification and increase the safety in treatment with eye drops. Methods: A first prototype was created with a material that enabled the addition of texture and odor features, and that was the materialized concept. With this prototype, we proceeded with a concept acceptance test to assess the receptivity of this solution by a group of 18 patients that were using 2 or more eye drops at that time. The patients answered a verbal survey after having contact with the sleeves on the eye drops presented by the investigator. After that, we conducted a concept effectivity test with 31 healthy volunteers that were blindfolded. This test consisted in four phases of tests with and without the sleeves prototype, to evaluate if the prototypes would help in the identification of eye drops. In the end, we tried to improve the prototype in order to meet more requirements that were pre-determined. Results: It was possible to develop the first prototype using silicon, a flexible material that can be adapted to many eye drop bottles available in the Brazilian market. In the concept acceptance test, 95% of the patients using two or more eye drops, most of them being elderly, declared that the sleeves would help identifying the eye drops and would help increasing the autonomy in the treatment with eye drops. In the concept effectivity test with 31 healthy volunteers, the sleeves increased the identification rate of eye drop bottles from 19% without the prototypes to 99% with the sleeves, in a setting where visual clues could not be used. We produced other four types of prototypes of sleeves made of silicon material but using different production techniques. Conclusion: It was possible to develop a prototype of sleeves to aid in the identification of eye drops. The multisensory sleeves prototype was well accepted by user of two or more eye drops and was effective in increasing the chance of identifying the eye drops in the tests we conducted. It was also possible to improve the prototypes and get to a final product.
- ItemAcesso aberto (Open Access)Métodos extrativos de mucilagem de semente de chia (Sálvia hispânica) para potencial uso em oftalmologia(Universidade Federal de São Paulo (UNIFESP), 2017-02-24) Gusmão, Roberto da Silva [UNIFESP]; Freitas, Denise de [UNIFESP]; http://lattes.cnpq.br/4036480252471491; http://lattes.cnpq.br/2908921235955460; Universidade Federal de São Paulo (UNIFESP)The mucilage are substances obtained some seeds, such as flax, chia, flax etc. These substances are rich in polysaccharides of high molecular weight and have essential oils, fatty acids and fiber. In oriental medicine, for example, chia seed has been used in various treatments. Among the treatments that chia seed is used in the control of cholesterol, obesity, food detoxification, increased gastric motility, reduction of cardiovascular risk, helps prevent premature aging and other benefits that are advocated in several published articles. The mucilage of plant origin are already established worldwide, mainly as vehicle laxative drugs. Thinking about the potential presented by the miraculous seed chia, the focus of this study is related to the choice of a cheap method of mucilage that produces seed with practical methods. It will be addressed in this work not only extractive methods for obtaining mucilage of chia seeds but will also be carried out physicochemical analyzes of mucilage obtained in the extraction process. Among the physicochemical studies in mucilage obtained include: pH, conductivity, sterility, heat resistance, osmolarity, viscosity and content, making it always the comparison with vehicles available in the market. Understand the physical and chemical characteristics of mucilage extracted from the seeds analyzed and understand its compatibility with the human body for potential use in medicine and especially in ophthalmology and the fundamental basis of this work.