Navegando por Palavras-chave "Pseudotumor cerebral"
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- ItemAcesso aberto (Open Access)Estenose bilateral de seio venoso transverso associado a papiledema: relato de caso(Conselho Brasileiro de Oftalmologia, 2003-06-01) Gouveia, Enéias Bezerra; Lobato, Frederico José Corrêa; Veras, José Filho De Sousa Lobão; Nunes, João Claudio; Muccioli, Cristina [UNIFESP]; Melo Filho, Agenor De; Real e Benemérita Sociedade Portuguesa de Beneficência Hospital São Joaquim Serviço de Oftalmologia; Universidade Federal de São Paulo (UNIFESP)The authors report the case of a female patient, 39 years old, presenting bilateral transverse venous sinus stenosis, associated with papilledema, visual acuity deficit and headache. Cerebral angiographic finding of bilateral transverse venous sinus stenosis elucidated the diagnosis. The patient was treated with cerebral angiographic stent implant, with consequent remission of ophthalmologic and neurological clinical findings.
- ItemAcesso aberto (Open Access)Fisiopatologia da cefaléia crônica diária: estudo do líquido cefalorraquidiano(Universidade Federal de São Paulo (UNIFESP), 2008-03-26) Vieira, Domingos Sávio de Souza [UNIFESP]; Peres, Mario Fernando Prieto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Introduction: Chronic daily headaches consist of a group of headaches, among them chronic migraine, that is comorbid with depression, overuse of medication, obesity and recently, cases of idiopathic intracranial hypertension without papilloedema. Objectives: To establish idiopathic intracranial hypertension without papilloedema prevalence and glutamate and gamma-aminobutyric acid levels in cerebrospinal fluid from patients with chronic migraine compared to other groups of patients. Methods: We studied patients with chronic migraine, who underwent lumbar puncture to rule out idiopathic intracranial hypertension without papilloedema. Amino acids glutamate and gamma-aminobutyric acid levels were measured by high performance liquid chromatography in cerebrospinal fluid. Results: Six patients, among sixty, had CSF open pressure higher than 200 mm H20 without papilloedema on fundoscopy. Patients who overused triptans had glutamate levels lower than those with abuse of other analgesic types and nonoverusers. The gamma-aminobutyric acid levels in cerebrospinal fluid were lower in depressed patients when compared to patients without depression and controls. Conclusions: The study of the cerebrospinal fluid was important in patients with chronic migraine for the exclusion of idiopathic intracranial hypertension without papilloedema, opening perspectives for the understanding of the physiopathology and development of new drug therapies for migraine and its comorbidities.
- ItemAcesso aberto (Open Access)Hipertensão intracraniana com manifestações oculares associada ao uso de tetraciclina: relato de caso(Conselho Brasileiro de Oftalmologia, 2005-10-01) Santos, Frederico Xavier Dos; Parolin, André [UNIFESP]; Lindoso, Elissandro Márcio Silva; Santos, Fernando Henrique Xavier; Sousa, Luciene Barbosa De [UNIFESP]; Hospital oftalmológico de Sorocaba; Universidade Federal de São Paulo (UNIFESP); Pontifícia Universidade Católica de SorocabaThe authors describe a young female patient with intracranial hypertension associated with ocular manifestations, during treatment with tetracycline. This is a rare adverse effect described in the medication warnings, and in a few reported cases in the scientific literature.
- ItemAcesso aberto (Open Access)Novo índice para avaliação da estenose dos seios transversos para diagnóstico de hipertensão intracraniana idiopática(Universidade Federal de São Paulo (UNIFESP), 2017-03-30) Carvalho, Gustavo Balthazar Da Silveira [UNIFESP]; Abdala, Nitamar [UNIFESP]; Matas, Sandro Luiz de Andrade [UNIFESP]; http://lattes.cnpq.br/7071172242012497; http://lattes.cnpq.br/8132921767941082; http://lattes.cnpq.br/1113728462867152; Universidade Federal de São Paulo (UNIFESP)Objective: To assess the role of venous magnetic resonance imaging (MRI) in the detection of transverse sinus stenosis and the importance of this finding in idiopathic intracranial hypertension (HII), and to propose an index that contributes to this diagnosis. METHODS: We retrospectively assessed the exams of patients over the age of 18 who were followed at our institution's pseudotumor ambulatory, who underwent intracranial venous ARM exams from January 2010 to July 2012. The exams were randomly analyzed by 3 radiologists. The evaluators classified the stenosis in the right and left transverse sinuses separately, according to the graduation: 0-normal; 1- Stenosis up to 1/3 (<33%); 2- Stenosis between 1/3 and 2/3 (33-66%); 3 - Stenosis above 2/3 (> 66%) and 4 - Hypoplasia or agenesis. We established an index based on the multiplication of the numbers of this degree of stenosis of each transverse sinus. Point and interval estimation of the sensitivity, specificity and area under the ROC curve were obtained to obtain cutoff points for the index in order to distinguish patient controls. Results: The sample selected in this study consisted of 63 individuals, 32 (50.8%) of the group with diagnosis of HII [31 (96.9%) women and only 1 (3.1%) men] and 31 ( 49.2%) of the control group. The HII group had a higher degree of stenosis when compared to the control group, for all examiners. Values greater than or equal to 4 for diagnosis of HII indicated a sensitivity of 94.7% and specificity of 93.5% Conclusion: We believe that MRA should be included in the evaluation of patients with suspected IBD and bilateral stenosis of the transverse sinus should be valued for diagnosis. The index proposed in this study to classify this stenosis proved to be a fast and accessible method for the diagnosis of IBD.