Navegando por Palavras-chave "Search human metapneumovirus"

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    Pesquisa de metapneumovirus em crianças portadoras de infecções respiratórias agudas atendidas em um hospital de urgência e emergência em Belém, Pará
    (Universidade Federal de São Paulo (UNIFESP), 2011-01-26) Rodrigues, Orlando da Gama [UNIFESP]; Carvalho, Werther Brunow de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: Clinical evaluation and research of viral (human metapneumovirus) of children under 5 years of age, suffering from ARI, and free search or referred to a hospital urgency and emergency in Belém, Pará. Method: A longitudinal prospective study from March 2008 to February 2009, we evaluated 67 samples of nasopharyngeal secretions of 67 patients with IRA - 29.9% patients with disease limited to the upper respiratory tract (DTRs) and 70.1% with lower respiratory tract disease (DTRI) and DTRs - through a chain reaction mediated by the polymerase reverse transcription (RT - PCR), real-time . Results: In the children studied were detected 13 cases (19.4%) were positive for human metapneumovirus. There was a higher percentage of viral identification in patients with DTRs associated with DTRI 61.5%, compared to patients with the disease limited to the upper tract (38.5%). In a univariate analysis where it was estimated the odds ratio for each of the variables, we observed that sex, days of illness, place of residence, family income, housing conditions, smoking, family history of asthma and the child, pneumonia in children, nutritional status, presence of fever, fatigue, cough and diagnosis were not statistically associated with HMPV (p < 0.05).In a multivariate analysis with(p<0,1), is verified that age(p=0,093) and prostration(p=0,063) showed statistically significant in the diagnosis of HMPV. Conclusion: The rate of detection of HMPV in this study, showed the presence of this virus, as prevalent etiologic agent in ARI in childhood, however, the clinical manifestations evaluated not showed statistical significance associated with HMPV. Further studies are needed, with greater coverage of viruses, using immunological rapid tests to increase the understanding of viral respiratory diseases, to elucidate the clinical aspects of the interaction of various viruses and to identify early cases potentially serious.