Navegando por Palavras-chave "Study Characteristics"

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    Características De Revisões Sistemáticas Cochrane Versus Revisões Sistemáticas Publicadas Em Revistas De Alto Fator De Impacto
    (Universidade Federal de São Paulo (UNIFESP), 2017-12-20) Porfirio, Gustavo Jose Martiniano [UNIFESP]; Riera, Rachel [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: The systematic review consists of the application of strategies that limit the risk of bias in the gathering, critical evaluation and synthesis of all relevant studies on a subject. It is considered as the best source of evidence for informed decision and has, as main aspects, clear eligibility criteria; explicit and reproducible methods; high sensitivity search looking for all relevant studies on the subject; critical appraisal of included studies; and systematic synthesis of the results of included studies. Despite the recent appreciation of systematic reviews and a significant increase in the number of publications with this design, there are several doubts about the quality of these publications in a global way. Although the limitations of using the impact factor for journal metrics, it is thought that the higher citation numbers of high impact factor journals identify that these reviews are as well executed as the Cochrane systematic reviews. Objective: To evaluate the characteristics of systematic reviews published in high impact factor journals compared to the reviews published in the Cochrane Database of Systematic Reviews regarding the presence of adequate content for critical appraisal of the publication. The hypothesis of this study was that the characteristics would be similar. Study design: A cross-sectional study. Sample: We included systematic reviews of the literature published in 2015 in journals of high impact factor or published by the Cochrane Collaboration. Outcomes: The primary outcomes were the characteristics of the systematic reviews based on PRISMA Statement and other complementary information. Statistical methods: No sample size calculation was performed. We analyzed all the systematic reviews published in high impact factor journals published in the year 2015 and their number was the criterion for defining the sample size of the other reviews (Cochrane reviews) included in the research. Results: Of the 134 studies included in the analyzes two groups studied (67 Cochrane and 67 journals of high impact factor), the following characteristics presented a significantly higher frequency in Cochrane reviews: a) provide at least one search strategy; b) does not restrict the search and / or selection of studies by language; c) do not use restriction of the search by year of publication; d) conduct the search for non-indexed studies; e) conducting the search in databases of clinical trials records; f) description duplicity for selection and extraction of data; g) description of method to resolve disagreements; h) description of the criteria for meta-analysis; and i) description of criteria for sensitivity or subgroup analysis; j) information on characteristics of excluded studies; l) information about ongoing studies; m) presentation of bias risk per study; n) indication of registration of the revision or of the existence of a previous protocol; o) presentation of a summary table of the findings; p) use of the GRADE approach; q) refer to the assessment of the quality of the evidence at the conclusion. Conclusion: Significant differences were observed between systematic reviews published by Cochrane and journals of high impact factor in relation to key items related to the quality of publications. The Cochrane publications presented a greater detail of the description of critical items in relation to the others, despite the lower number of gross citations observed in the sample and the lower impact factor in relation to the periodicals analyzed
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    Perfil dos estudos do departamento de ginecologia submetidos ao comitê de ética em pesquisa (CEP) da Unifesp no período de 2001 a 2012 com o objetivo de obtenção de títulos
    (Universidade Federal de São Paulo (UNIFESP), 2016-03-31) Meleti, Andreia Reis Pereira [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; http://lattes.cnpq.br/0973903299568770; http://lattes.cnpq.br/9556953803642953; Universidade Federal de São Paulo (UNIFESP)
    Objective: To determine the profile of the studies submitted to the Department of Gynecology at Unifesp, the institutional Ethics Committee from 2001 to 2012. Casuistry andMethods:This study was conducted in the Department of Gynecology, Universidade Federal de São Paulo. They were raised all research projects submitted to the Comitê de Ética em Pesquisaof UNIFESP between 2001 to 2012. Some specific characteristics were considered of each study as stratification by group according to specification resolution 466 of Conselho Nacional de Saúde(CNS), group characteristics, such as whether the study is a protocol of prospective or retrospective research, funding agency and academic goal. The data were tabulated in Excel table and presented in graphs. We analyzed all studies submitted in the period, a total of 590 studies already determined.Results:The results were presented through tables and graphs, and discussed at the end of the study.Conclusions:The knowledge of the profile and the ethical implications indicated by the Ethics Committee in these studies may contribute to future research projects,so that they may be designed more appropriately by their researchers.