Navegando por Palavras-chave "science"

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    Articles with authors affiliated to Brazilian institutions published from 1994 to 2003 with 100 or more citations: I - The weight of international collaboration and the role of the networks
    (Acad Brasileira De Ciencias, 2006-12-01) Packer, Abel Laerte; Meneghini, Rogerio [UNIFESP]; WHO; Universidade Federal de São Paulo (UNIFESP)
    Articles with 100 citations or more in the scientific literature and with at least one author with Brazilian affiliation, were identified in the Thomson-ISI (Institute for Scientific Information) Web of Science bibliometric database, covering a 10-year period, from 1994 to 2003; 248 (0.23%) out of a total of 109,916 articles with Brazilian affiliation were identified. This study was primarily carried out to identify thematic nuclei of excellence in research that had major impact in the international literature (Meneghini and Packer 2006). The regional and institutional affiliation distributions of these articles follow approximately that of the total of Brazilian articles in the ISI database. However, some significant deviations are observed derived from the outstanding performance of a few groups responsible for the publication of the HC-ISI (Highly cited ISI) papers. The international collaboration and the network organization of work played a fundamental role in these results. It is evident that the role played by organizations in research networks as well as the international collaborations exerted strong influence, in the impact of these articles, although with distinct amplitude in the different fields.
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    Articles with authors affiliated to Brazilian institutions published from 1994 to 2003 with 100 or more citations: II - Identification of thematic nuclei of excellence in Brazilian science
    (Acad Brasileira de Ciencias, 2006-12-01) Meneghini, Rogerio [UNIFESP]; Packer, Abel Laerte [UNIFESP]; WHO; Universidade Federal de São Paulo (UNIFESP)
    Articles with 100 citations or more in the scientific literature and with at least one author with Brazilian affiliation, were identified in the Thomson-ISI (Institute for Scientific Information) Web of Science bibliometric database covering a 10-year period, from 1994 to 2003 (see Packer and Meneghini 2006); 248 (0.23%) out of a total of 109,916 articles with Brazilian affiliation were identified. This study was primarily carried out to identify thematic nuclei of excellence in research that had major impact in the international literature. Twelve of these nuclei in the fields of Biomedicine, Medicine, Biology, Physic, Chemistry and Astronomy were considered outstanding and their genesis and development were described. the weight of factors such as international collaboration and network organization are distinct in these areas and the reasons for that are discussed.
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    A dívida de Hume com Pascal
    (Faculdade de Filosofia e Ciências Humanas da UFMG, 2011-12-01) Smith, Plinio Junqueira [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Though neglected by Humean scholars, Pascal's thoughts seem to be very important to Hume in many ways and along all his life. This paper focus more on epistemological and matephysical matters, than on morals or religion. Hume uses some of Pascal's ideas concerning scepticism and arguments concerning the cogito and the Cartesian view of science.
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    Immunophenotypic Profile and Increased Risk of Hospital Admission for Infection in Infants Born to Female Kidney Transplant Recipients
    (Wiley-Blackwell, 2015-06-01) Ono, E. [UNIFESP]; Santos, A. M. dos [UNIFESP]; Viana, P. O. [UNIFESP]; Dinelli, M. I. S. [UNIFESP]; Sass, N. [UNIFESP]; De Oliveira, L. [UNIFESP]; Goulart, A. L. [UNIFESP]; Moraes-Pinto, M. I. de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Children born to female kidney recipients are exposed to immunosuppressive drugs during gestation. Little is known about their immune system at birth or in the long term. Twenty-eight children born to female kidney recipients and 40 full-term children born to healthy mothers were evaluated. T, B, NK, NKT, T cells were assessed by flow cytometry and functional evaluation of T and dendritic cells after in vitro activation was performed at birth and at 8 months of age. At birth, infants born to female kidney recipients showed lower numbers of CD4+ T, NKT and intense reduction of B cells (median cells/mm(3), transplant: 153.7 X control: 512.4; p<0.001). There was also a reduced percentage of activated CD8+ T and of CD4+ regulatory T cells. Activated memory and exhausted memory B cells showed higher percentages among children exposed to immunosuppressors when compared to control group. At 8 months, most immune alterations were no longer observed, but four children still had low numbers of some lymphocyte subsets at this age. Children born to female kidney recipients had 4.351 (95% CI: 1.026-15.225; p=0.046) higher risk of hospital admission in the first months of lifesome, with severe clinical manifestationsthan those born to healthy women.