Nomogram of fetal middle cerebral artery peak systolic velocity at 23-35 weeks of gestation in a Brazilian population: Pilot study

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dc.contributor.authorMachado Nardozza, Luciano Marcondes [UNIFESP]
dc.contributor.authorSimioni, Christiane [UNIFESP]
dc.contributor.authorGarbato, Gabriel [UNIFESP]
dc.contributor.authorAraujo Junior, Edward [UNIFESP]
dc.contributor.authorGuimaraes Filho, Helio Antonio [UNIFESP]
dc.contributor.authorTorloni, Maria Regina [UNIFESP]
dc.contributor.authorCamano, Luiz [UNIFESP]
dc.contributor.authorMoron, Antonio Fernandes [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:49:26Z
dc.date.available2016-01-24T13:49:26Z
dc.date.issued2008-01-01
dc.description.abstractObjective. To establish normative data for the peak systolic velocity of the middle cerebral artery (MCA-PSV) of fetuses in the second half of pregnancy using multiples of the median and percentile reference range. Methods. A cross-sectional study was performed in 90 healthy fetuses at between 23 and 35 weeks of gestation. A bi-dimensional axial scan of the brain, including the thalami and cavitas septi pellucidi was obtained. the circle of Willis was visualized using color flow mapping. Pulsed-wave Doppler velocimetry of the MCA was performed close to the artery's origin, with a beam-vessel angle below 20. A table with the multiples of the median (MoM) of the MCA-PSV for each gestational age was generated and Pearson's correlation coefficient (r) was calculated. Regression modeling across gestational age was performed to obtain the reference values. Results. There was a strong correlation between the MCA-PVS and gestational age (r=0.70; p0.001). Values for the MCA-PSV for the following MoM were calculated: 1.0, 1.29, 1.50, and 1.55. the MCA-PSV 2.5th and 97.5th centiles ranged from 24.33cm2/s to 78.36cm2/s, respectively, between weeks 23 and 35. Conclusions. A nomogram for the fetal MCA-PSV during the second half of pregnancy was generated.en
dc.description.affiliationUniversidade Federal de São Paulo, EPM, Dept Obstet, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, EPM, Dept Obstet, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent714-718
dc.identifierhttp://dx.doi.org/10.1080/14767050802215243
dc.identifier.citationJournal of Maternal-fetal & Neonatal Medicine. Abingdon: Taylor & Francis Ltd, v. 21, n. 10, p. 714-718, 2008.
dc.identifier.doi10.1080/14767050802215243
dc.identifier.issn1476-7058
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30337
dc.identifier.wosWOS:000260925500004
dc.language.isoeng
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal of Maternal-fetal & Neonatal Medicine
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.subjectFetusen
dc.subjectDoppler ultrasonographyen
dc.subjectmiddle cerebral arteryen
dc.subjectnomogramen
dc.titleNomogram of fetal middle cerebral artery peak systolic velocity at 23-35 weeks of gestation in a Brazilian population: Pilot studyen
dc.typeinfo:eu-repo/semantics/article
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