Can the Induction of Labor with Misoprostol Increase Maternal Blood Loss?

dc.citation.issue2
dc.citation.volume39
dc.contributor.authorPraciano Souza, Paulo Cesar
dc.contributor.authorAzevedo Damasceno, Karla Santana
dc.contributor.authorAraujo Junior, Edward [UNIFESP]
dc.contributor.authorAlencar Junior, Carlos Augusto
dc.contributor.authorde Lucena Feitosa, Francisco Edson
dc.coverageRio De Janeiro Rj
dc.date.accessioned2020-07-17T14:03:00Z
dc.date.available2020-07-17T14:03:00Z
dc.date.issued2017
dc.description.abstractPurpose To evaluate blood loss during misoprostol-induced vaginal births and during cesarean sections after attempted misoprostol induction. Methods We conducted a prospective observational study in 101 pregnant women indicated for labor inductionen
dc.description.abstractpre-and postpartum hemoglobin levels were measured to estimate blood loss during delivery. Labor was induced by administering 25 mu g vaginal misoprostol every 6 hours (with a maximum of 6 doses). The control group included 30 patients who spontaneously entered labor, and 30 patients who underwent elective cesarean section. Pre-and postpartum hemoglobin levels were evaluated using the analysis of variance for repeated measurements, showing the effects of time (pre-and postpartum) and of the group (with and withoutmisoprostol administration). Results Therewere significant differences between pre-and postpartum hemoglobin levels (p < 0.0001) with regard to misoprostol-induced vaginal deliveries (1.6 +/- 1.4 mg/dL), non-induced vaginal deliveries (1.4 +/- 1.0 mg/dL), cesarean sections after attempted misoprostol induction (1.5 +/- 1.0 mg/dL), and elective cesarean deliveries (1.8 +/- 1.1 mg/dL). However, the differences were proportional between the groups with and without misoprostol administration, for both cesarean (p = 0.6845) and vaginal deliveries (p = 0.2694). Conclusions Labor induction using misoprostol did not affect blood loss during delivery.en
dc.description.affiliationUniv Fed Ceara, Maternidade Escola Assis Chateaubriand, Obstet Sect, Fortaleza, Ceara, Brazil
dc.description.affiliationUniv Fed Sao Paulo EPM UNIFESP, Escola Paulista Med, Dept Obstet, Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo EPM UNIFESP, Escola Paulista Med, Dept Obstet, Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent53-59
dc.identifierhttp://dx.doi.org/10.1055/s-0037-1598640
dc.identifier.citationRevista Brasileira De Ginecologia E Obstetricia. Rio De Janeiro Rj, v. 39, n. 2, p. 53-59, 2017.
dc.identifier.doi10.1055/s-0037-1598640
dc.identifier.fileWOS000410251700003.pdf
dc.identifier.issn0100-7203
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55126
dc.identifier.wosWOS:000410251700003
dc.language.isoeng
dc.publisherFederacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo
dc.relation.ispartofRevista Brasileira De Ginecologia E Obstetricia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectinduced laboren
dc.subjectmisoprostolen
dc.subjectpostpartum hemorrhageen
dc.subjecthemoglobinen
dc.subjectvaginal birthen
dc.titleCan the Induction of Labor with Misoprostol Increase Maternal Blood Loss?en
dc.typeinfo:eu-repo/semantics/article
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