Randomized Controlled Trial of Iron-Fortified Drinking Water in Preschool Children

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dc.contributor.authorArcanjo, Francisco Placido Nogueira [UNIFESP]
dc.contributor.authorAmancio, Olga Maria Silverio [UNIFESP]
dc.contributor.authorBraga, Josefina Aparecida Pellegrini [UNIFESP]
dc.contributor.authorPinto, Vicente de Paulo Teixeira
dc.contributor.institutionFree Univ Brussels
dc.contributor.institutionPrime Hlth Consultants Inc
dc.contributor.institutionUniv Pittsburgh
dc.contributor.institutionBaylor Univ
dc.contributor.institutionUniv Queensland
dc.contributor.institutionHosp ABC Mexico
dc.contributor.institutionMiami Childrens Hosp
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionInst Nacl Salud
dc.contributor.institutionUniv Seville
dc.contributor.institutionPonce Sch Med
dc.contributor.institutionUniv Nebraska
dc.contributor.institutionUniv Hong Kong
dc.contributor.institutionMead Johnson Res Ctr
dc.date.accessioned2018-06-18T10:46:21Z
dc.date.available2018-06-18T10:46:21Z
dc.date.issued2010-04-01
dc.description.abstractObjectives: To evaluate the effects of fortified drinking water. with different concentrations of iron added, on hemoglobin and hematocrit values in preschoolers.Methods: Double-blind, randomized cluster clinical trial, with children aged 2 to 5 years of age, from 4 state-run schools, forming 1 group for each school. For fortification, ferrous sulphate in concentrations of 5 mg of elemental iron per liter of water (group A), 7.5 mg (group B), and 10 mg (group C), was used during a period of 4 months. In group D, the control, a placebo (Bixa orellana) was added. Hemoglobin and hematocrit values were checked before and after intervention.Results: Before fortification, hemoglobin and hematocrit averages were below the reference values adopted in all groups. After fortification, the prevalence of anemia showed a reduction in the 4 groups, which was more pronounced in group B, at 48.3%. The hemoglobin values in groups B (11.5) and C (11.4) were statistically similar. However, the average consumption of water/day/student was lower in group C. Comparison of hemoglobin values between groups A (11.2) and D (11.0) did not show a significant difference, suggesting insignificant efficacy with 5 mg Fe/L fortification.Conclusions: The consumption of drinking water fortified with 7.5 mg of elemental iron/L water resulted in greater adhesion and an increase in hemoglobin values, with a reduction in the prevalence of anemia.en
dc.description.affiliationUniv Fed Ceara, Dept Pediat, Sobral Unit, Sobral, Ceara, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pediat, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Pediat, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFUNCAP-Fundacao Cearense de Apoio ao Desenvolvimento Cientifico
dc.format.extent308-316
dc.identifierhttp://dx.doi.org/10.1080/07315724.2010.10719825
dc.identifier.citationJournal Of The American College Of Nutrition. Abingdon: Routledge Journals, Taylor & Francis Ltd, v. 29, n. 2, p. 122-129, 2010.
dc.identifier.doi10.1080/07315724.2010.10719825
dc.identifier.issn0731-5724
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/44720
dc.identifier.wosWOS:000281124600006
dc.language.isoeng
dc.publisherRoutledge Journals, Taylor & Francis Ltd
dc.relation.ispartofJournal Of The American College Of Nutrition
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.subjectironen
dc.subjectpotable wateren
dc.subjectpreschool childrenen
dc.subjecthemoglobinen
dc.subjectanemiaen
dc.titleRandomized Controlled Trial of Iron-Fortified Drinking Water in Preschool Childrenen
dc.typeinfo:eu-repo/semantics/article
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